Overview

  • Product name
    Anti-Mucin 5AC antibody [45M1], prediluted
    See all Mucin 5AC primary antibodies
  • Description
    Mouse monoclonal [45M1] to Mucin 5AC, prediluted
  • Host species
    Mouse
  • Tested applications
    Suitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse
  • Immunogen

    Tissue, cells or virus corresponding to Mouse Mucin 5AC. M1 mucin preparation from the fluid of an ovarian mucinous cyst.
    Database link: P98088

  • Positive control
    • IHC-P: Human stomach, stomach adenocarcinoma and colon adenocarcinoma tissues.
  • General notes

    For manual IHC only.

Properties

Applications

Our Abpromise guarantee covers the use of ab28372 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/1.

Ready to use.

Primary antibody incubation for 30 minutes at room temperature.

Target

  • Relevance
    Mucins are high molecular weight glycoproteins with 80% carbohydrates and 20% core protein. Gastric Mucin 5AC antigen is found in columnar mucus cells of surface gastric epithelium and in goblet cells of the fetal and precancerous colon but not in normal colon. Resurgence of gastric mucin during colonic carcinogenesis is suggestive of either re-expression of the peptide core of gastric mucin in the adult colon or due to changes in the glycosylation pattern of mucin, which expose the hidden Mucin 5AC antigen.
  • Cellular localization
    Secreted; Cytoplasmic and cell surface
  • Database links
  • Alternative names
    • Apomucin antibody
    • Apomucin Major Airway Glycoprotein antibody
    • Gastric mucin antibody
    • LeB antibody
    • Lewis B blood group antigen antibody
    • Major Airway Glycoprotein antibody
    • MUC 5 antibody
    • MUC5 antibody
    • MUC5AC antibody
    • Mucin 5 subtype AC tracheobronchial antibody
    • Mucin 5 Subtypes A And C antibody
    • Mucin 5 subtypes A and C tracheobronchial/gastric antibody
    • Mucin 5, tracheobronchial/gastric antibody
    • Mucin 5AC antibody
    • Mucin 5AC oligomeric mucus/gel forming antibody
    • Mucin 5AC, oligomeric mucus/gel forming pseudogene antibody
    • Mucin antibody
    • TBM antibody
    • Tracheobronchial Mucin (TBM) antibody
    • Tracheobronchial mucin antibody
    see all

Images

  • Formalin-fixed, paraffin-embedded human stomach tissue stained for Mucin 5AC using ab28372 in immunohistochemical analysis.

  • Formalin-fixed, paraffin-embedded human stomach adenocarcinoma tissue stained for Mucin 5AC using ab28372 in immunohistochemical analysis.

  • Formalin-fixed, paraffin-embedded human colon adenocarcinoma tissue stained for Mucin 5AC using ab28372 in immunohistochemical analysis.

  • Formalin-fixed, paraffin-embedded human stomach tissue stained for Mucin 5AC using ab28372 in immunohistochemical analysis.

References

ab28372 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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