Anti-MUM1 antibody (ab228442)
- Datasheet
- References
- Protocols
Overview
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Product name
Anti-MUM1 antibody
See all MUM1 primary antibodies -
Description
Rabbit polyclonal to MUM1 -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human -
Immunogen
Recombinant fragment corresponding to Human MUM1 aa 52-278.
Database link: Q2TAK8 -
Positive control
- WB: Jurkat and Ramos cell lysates.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
Preservative: 0.05% Sodium azide
Constituents: PBS, 0.05% BSA -
Concentration information loading... -
Purity
Protein A purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
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Recombinant Protein
Applications
Our Abpromise guarantee covers the use of ab228442 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| WB | Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 79 kDa. |
Target
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Function
Involved in the DNA damage response pathway by contributing to the maintenance of chromatin architecture. Recruited to the vicinity of DNA breaks by TP53BP1 and plays an accessory role to facilitate damage-induced chromatin changes and promoting chromatin relaxation. Required for efficient DNA repair and cell survival following DNA damage. -
Sequence similarities
Belongs to the MUM1 family.
Contains 1 PWWP domain. -
Domain
The PWWP domain mediates the interaction with nucleosomes. -
Post-translational
modificationsPhosphorylated upon DNA damage, probably by ATM or ATR. -
Cellular localization
Nucleus. Recuited to DNA damage sites via its interaction with the BRCT domain of TP53BP1. - Information by UniProt
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Database links
- Entrez Gene: 84939 Human
- Omim: 601900 Human
- SwissProt: Q2TAK8 Human
- Unigene: 515016 Human
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Alternative names
- EXPAND1 antibody
- FLJ14868 antibody
- FLJ22283 antibody
see all
Images
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Western blot - Anti-MUM1 antibody (ab228442)All lanes : Anti-MUM1 antibody (ab228442) at 1 µg/ml
Lane 1 : Jurkat (human T cell leukemia cell line from peripheral blood) cell lysate
Lane 2 : Ramos (human Burkitt's lymphoma cell line) cell lysate
Predicted band size: 79 kDa
Datasheets and documents
References
ab228442 has not yet been referenced specifically in any publications.
