Key features and details
- Rabbit polyclonal to Munc18c
- Suitable for: IHC-P, WB
- Reacts with: Mouse, Human
- Isotype: IgG
Product nameAnti-Munc18c antibody
See all Munc18c primary antibodies
DescriptionRabbit polyclonal to Munc18c
Tested applicationsSuitable for: IHC-P, WBmore details
Species reactivityReacts with: Mouse, Human
Recombinant fragment corresponding to Human Munc18c aa 266-528.
NDTYKYKTDGKEKEAILEEEDDLWVRIRHRHIAVVLEEIPKLMKEISSTK KATEGKTSLSALTQLMKKMPHFRKQITKQVVHLNLAEDCMNKFKLNIEKL CKTEQDLALGTDAEGQKVKDSMRVLLPVLLNKNHDNCDKIRAILLYIFSI NGTTEENLDRLIQNVKIENESDMIRNWSYLGVPIVPQSQQGKPLRKDRSA EETFQLSRWTPFIKDIMEDAIDNRLDSKEWPYCSQCPAVWNGSGAVSARQ KPRANYLEDRKNG
Database link: O00186
- WB: Mouse kidney tissue lysate. IHC-P: Human adrenal gland tissue.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.40
Constituents: 50% Glycerol (glycerin, glycerine), PBS, 0.03% Proclin 300
Concentration information loading...
PurityProtein G purified
Our Abpromise guarantee covers the use of ab224625 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||1/20 - 1/200.|
|WB||1/500 - 1/5000. Detects a band of approximately 68 kDa (predicted molecular weight: 68 kDa).|
FunctionTogether with STX4 and VAMP2, may play a role in insulin-dependent movement of GLUT4 and in docking/fusion of intracellular GLUT4-containing vesicles with the cell surface in adipocytes.
Tissue specificityMegakaryocytes and platelets.
Sequence similaritiesBelongs to the STXBP/unc-18/SEC1 family.
modificationsPhosphorylated by PKC in platelets in response to thrombin stimulation; phosphorylation inhibits binding to STX4.
Cellular localizationCytoplasm > cytosol. Cell membrane. In platelets, predominantly cytosolic. Low amounts membrane-associated.
- Information by UniProt
- Munc18 3 antibody
- Munc18 c antibody
- Platelet Sec1 protein antibody
Anti-Munc18c antibody (ab224625) at 1/500 dilution + Mouse kidney tissue lysate
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 68 kDa
Observed band size: 68 kDa
Paraffin-embedded human adrenal gland tissue stained for Munc18c using ab224625 at 1/100 dilution in immunohistochemical analysis.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab224625 has not yet been referenced specifically in any publications.