Overview

  • Product name

    Anti-Musashi 1 / Msi1 antibody
    See all Musashi 1 / Msi1 primary antibodies
  • Description

    Rabbit polyclonal to Musashi 1 / Msi1
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Mouse
    Predicted to work with: Rat, Human
  • Immunogen

    Synthetic peptide within Human Musashi 1/ Msi1 aa 60-110 conjugated to keyhole limpet haemocyanin. The exact sequence is proprietary.
    Database link: O43347

  • Positive control

    • IHC-P: Mouse brain and pancreas tissues.

Properties

Applications

Our Abpromise guarantee covers the use of ab218189 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/100 - 1/500.

Target

  • Function

    RNA binding protein that regulates the expression of target mRNAs at the translation level. Regulates expression of the NOTCH1 antagonist NUMB. Binds RNA containing the sequence 5'-GUUAGUUAGUUAGUU-3' and other sequences containing the pattern 5'-[GA]U(1-3)AGU-3'. May play a role in the proliferation and maintenance of stem cells in the central nervous system.
  • Tissue specificity

    Detected in fetal kidney, brain, liver and lung, and in adult brain and pancreas. Detected in hepatoma cell lines.
  • Sequence similarities

    Belongs to the Musashi family.
    Contains 2 RRM (RNA recognition motif) domains.
  • Domain

    The first RNA recognition motif binds more strongly to RNA compared to the second one.
  • Cellular localization

    Cytoplasm. Nucleus.
  • Information by UniProt
  • Database links

  • Alternative names

    • Msi 1 antibody
    • Msi1 antibody
    • MSI1H_HUMAN antibody
    • Musashi homolog 1 antibody
    • Musashi RNA binding protein 1 antibody
    • Musashi-1 antibody
    • Musashi1 antibody
    • RNA binding protein Musashi homolog 1 antibody
    • RNA-binding protein Musashi homolog 1 antibody
    see all

Images

  • Formalin-fixed, paraffin-embedded mouse pancreas tissue stained for Musashi 1 / Msi1 using ab218189 at 1/200 dilution in immunohistochemical analysis, followed by conjugation to the secondary antibody and DAB staining.

  • Formalin-fixed, paraffin-embedded mouse brain tissue stained for Musashi 1 / Msi1 using ab218189 at 1/200 dilution in immunohistochemical analysis, followed by conjugation to the secondary antibody and DAB staining.

References

ab218189 has not yet been referenced specifically in any publications.

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