Key features and details
- Rabbit polyclonal to Muscarinic Acetylcholine Receptor 1/CHRM1 - Cytoplasmic domain
- Reacts with: Mouse, Rat, Human
- Isotype: IgG
Product nameAnti-Muscarinic Acetylcholine Receptor 1/CHRM1 antibody - Cytoplasmic domain
See all Muscarinic Acetylcholine Receptor 1/CHRM1 primary antibodies
DescriptionRabbit polyclonal to Muscarinic Acetylcholine Receptor 1/CHRM1 - Cytoplasmic domain
Species reactivityReacts with: Mouse, Rat, Human
Predicted to work with: Pig, Rhesus monkey, Orangutan
Recombinant fragment corresponding to Human Muscarinic Acetylcholine Receptor 1/CHRM1 aa 210-366.
RIYRETENRARELAALQGSETPGKGGGSSSSSERSQPGAEGSPETPPGRC CRCCRAPRLLQAYSWKEEEEEDEGSMESLTSSEGEEPGSEVVIKMPMVDP EAQAPTKQPPRSSPNTVKRPTKKGRDRAGKGQKPRGKEQLAKRKTFSLVK EKKAART
Database link: P11229
- HepG2 cell line extract.
This product was previously labelled as Muscarinic Acetylcholine Receptor 1
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 50% Glycerol, 49% PBS
Concentration information loading...
PurityProtein A purified
RelevanceThe muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 1 is involved in mediation of vagally-induced bronchoconstriction and in the acid secretion of the gastrointestinal tract. Muscarinic receptors are so called as they are more sensitive to the effects of the alkaloid muscarine, rather than nicotine.
Cellular localizationCell Membrane; multi-pass membrane protein
- AChR antibody
- Cholinergic receptor muscarinic 1 antibody
- CHRM1 antibody
ab180636 has been referenced in 2 publications.
- Tarafder S et al. A Combination of Oxo-M and 4-PPBP as a potential regenerative therapeutics for tendon injury. Theranostics 9:4241-4254 (2019). PubMed: 31281545
- Wei W et al. Muscarinic cholinergic signaling and overactive bladder-like symptoms associated with invasive bladder cancer. Oncol Lett 16:775-784 (2018). PubMed: 29963145