Anti-Muscarinic Acetylcholine Receptor M5 antibody (ab41171)


  • Product name
    Anti-Muscarinic Acetylcholine Receptor M5 antibody
    See all Muscarinic Acetylcholine Receptor M5 primary antibodies
  • Description
    Rabbit polyclonal to Muscarinic Acetylcholine Receptor M5 - Carboxyterminal end
  • Host species
  • Specificity
    Cross reactivity: M5 Muscarinic Receptor (519-531): 100% M5 Muscarinic Receptor: 75% No cross reactivity was observed in: M1 Muscarinic Receptor(451-460) M1 Muscarinic Receptor M2 Muscarinic Receptor(457-466) M2 Muscarinic Receptor M3 Muscarinic Receptor(580-589) M3 Muscarinic Receptor M4 Muscarinic Receptor(469-478) M4 Muscarinic Receptor
  • Tested applications
    Suitable for: WB, ELISA, IHC (PFA fixed), IHC-FoFrmore details
  • Species reactivity
    Reacts with: Rat
  • Immunogen

    Synthetic peptide analogue of the C terminal of rat muscarinic M5 receptor covalently attached onto a carrier protein.

  • Positive control
    • Rat brain tissue, whole brain homogenate and cultured cells.



Our Abpromise guarantee covers the use of ab41171 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/400. Predicted molecular weight: 60 kDa. Blocking with 5% goat or donkey serum significantly reduces background when compared with BSA or milk blocking.
ELISA Use at an assay dependent concentration.
IHC (PFA fixed) 1/400.
IHC-FoFr Use at an assay dependent concentration. PubMed: 23773170


  • Relevance
    The muscarinic acetylcholine receptor M5 is a member of the GPCR family (subfamily, acetylcholine) which mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. The rimary transducing effect is PI turnover. The receptor has been reported to be expressed in blood, brain, and ovary. ESTs have been isolated from human testis and placenta libraries.
  • Cellular localization
    Membrane; multi-pass membrane protein.
  • Database links
  • Alternative names
    • Acetylcholine receptor muscarinic 5 antibody
    • AChR antibody
    • AChR M5 antibody
    • CHKM5MR antibody
    • Cholinergic receptor muscarinic 5 antibody
    • Chrm 5 antibody
    • CHRM5 antibody
    • HM 5 antibody
    • HM5 antibody
    • m5 antibody
    • M5R antibody
    • MGC41838 antibody
    see all


This product has been referenced in:
  • Zhu H  et al. Impairments of spatial memory in an Alzheimer's disease model via degeneration of hippocampal cholinergic synapses. Nat Commun 8:1676 (2017). Read more (PubMed: 29162816) »
  • Muschter D  et al. Reactivity of rat bone marrow-derived macrophages to neurotransmitter stimulation in the context of collagen II-induced arthritis. Arthritis Res Ther 17:169 (2015). IF . Read more (PubMed: 26104678) »

See all 4 Publications for this product

Customer reviews and Q&As

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Leider bieten wir generell keine kostenlosen Proben zu Testzwecken an. Hier bei Abcam verfahren wir so, dass wir einen kostenlosen Ersatz oder eine Gutschrift verschicken, falls ein Antikörper nicht so...

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I have not been able to obtain any images of this antibody using in tissue staining, and I am sorry that we don't have these available. <...

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Thank you for contacting us with your question.

I've looked through our records andto our knowledge, the antibody has only been tested inWestern blot, ELISA, and IHC on standard PFA-fixed tissue. I will get in touch with the lab and request i...

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