Key features and details
- Rabbit polyclonal to Muscarinic Acetylcholine Receptor M5/CHRM5
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
Product nameAnti-Muscarinic Acetylcholine Receptor M5/CHRM5 antibody
See all Muscarinic Acetylcholine Receptor M5/CHRM5 primary antibodies
DescriptionRabbit polyclonal to Muscarinic Acetylcholine Receptor M5/CHRM5
SpecificityBLAST analysis of the peptide immunogen showed no homology with other human proteins.
Tested applicationsSuitable for: IHC-Pmore details
Species reactivityReacts with: Human
Predicted to work with: Chimpanzee, Monkey, Gorilla, Common marmoset
Synthetic peptide corresponding to Human Muscarinic Acetylcholine Receptor M5/CHRM5. Synthetic peptide corresponding to a 16 amino acid region within the 3rd cytoplasmic domain of Human Muscarinic Acetylcholine Receptor M5/CHRM5.
Database link: P08912
- Human brain tissue.
This product was previously labelled as Muscarinic Acetylcholine Receptor M5
Storage instructionsShipped at 4°C.
Storage bufferPreservative: 0.1% Sodium azide
Constituent: 99% PBS
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab150531 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||Use a concentration of 6 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.|
FunctionThe muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover.
Sequence similaritiesBelongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily. CHRM5 sub-subfamily.
Cellular localizationCell membrane. Cell junction, synapse, postsynaptic cell membrane.
- Information by UniProt
- Acetylcholine receptor muscarinic 5 antibody
- AChR antibody
- AChR M5 antibody
ab150531 has been referenced in 1 publication.
- Wei W et al. Muscarinic cholinergic signaling and overactive bladder-like symptoms associated with invasive bladder cancer. Oncol Lett 16:775-784 (2018). PubMed: 29963145