Overview

  • Product name

    Anti-Muscarinic Acetylcholine Receptor M5/CHRM5 antibody
    See all Muscarinic Acetylcholine Receptor M5/CHRM5 primary antibodies
  • Description

    Rabbit polyclonal to Muscarinic Acetylcholine Receptor M5/CHRM5
  • Host species

    Rabbit
  • Specificity

    BLAST analysis of the peptide immunogen showed no homology with other human proteins.
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Chimpanzee, Monkey, Gorilla, Common marmoset
  • Immunogen

    Synthetic peptide corresponding to Human Muscarinic Acetylcholine Receptor M5/CHRM5. Synthetic peptide corresponding to a 16 amino acid region within the 3rd cytoplasmic domain of Human Muscarinic Acetylcholine Receptor M5/CHRM5.
    Database link: P08912

  • Positive control

    • Human brain tissue.
  • General notes

     This product was previously labelled as Muscarinic Acetylcholine Receptor M5

     

Properties

Applications

Our Abpromise guarantee covers the use of ab150531 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 6 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function

    The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover.
  • Sequence similarities

    Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily. CHRM5 sub-subfamily.
  • Cellular localization

    Cell membrane. Cell junction, synapse, postsynaptic cell membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • Acetylcholine receptor muscarinic 5 antibody
    • AChR antibody
    • AChR M5 antibody
    • ACM5_HUMAN antibody
    • CHKM5MR antibody
    • Cholinergic receptor muscarinic 5 antibody
    • Chrm 5 antibody
    • Chrm5 antibody
    • HM 5 antibody
    • HM5 antibody
    • m5 antibody
    • M5R antibody
    • MGC41838 antibody
    • Muscarinic acetylcholine receptor M5 antibody
    see all

Images

  • Immunohistochemical analysis of formalin fixed, paraffin embedded Human brain tissue (vessel) labeling Muscarinic Acetylcholine Receptor M5/CHRM5 with ab150531 at 6 µg/ml.

References

This product has been referenced in:

  • Wei W  et al. Muscarinic cholinergic signaling and overactive bladder-like symptoms associated with invasive bladder cancer. Oncol Lett 16:775-784 (2018). Read more (PubMed: 29963145) »
See 1 Publication for this product

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