Key features and details
- Potent, selective GABAA agonist
- CAS Number: 2763-96-4
- Purity: > 99%
- Soluble in water to 100 mM
- Form / State: Solid
- Source: Synthetic
Product nameMuscimol, GABAA agonist
DescriptionPotent, selective GABAA agonist
Potent, selective GABAA agonist.
Also available in simple stock solutions (ab146673) - add 1 ml of water to get an exact, ready-to-use concentration.
Storage instructionsStore at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Solubility overviewSoluble in water to 100 mM
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab120094 has been referenced in 17 publications.
- Estebanez L et al. Parvalbumin-Expressing GABAergic Neurons in Primary Motor Cortex Signal Reaching. Cell Rep 20:308-318 (2017). PubMed: 28700934
- Koga K et al. Chemogenetic silencing of GABAergic dorsal horn interneurons induces morphine-resistant spontaneous nocifensive behaviours. Sci Rep 7:4739 (2017). PubMed: 28680103
- Langer TM et al. Effects on breathing of agonists to µ-opioid or GABAA receptors dialyzed into the ventral respiratory column of awake and sleeping goats. Respir Physiol Neurobiol 239:10-25 (2017). PubMed: 28137700
- Heubl M et al. GABAA receptor dependent synaptic inhibition rapidly tunes KCC2 activity via the Cl--sensitive WNK1 kinase. Nat Commun 8:1776 (2017). PubMed: 29176664
- Zonouzi M et al. GABAergic regulation of cerebellar NG2 cell development is altered in perinatal white matter injury. Nat Neurosci 18:674-82 (2015). PubMed: 25821912