Anti-MYBBP1A antibody (ab89121)
Key features and details
- Mouse polyclonal to MYBBP1A
- Suitable for: WB, ICC/IF
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-MYBBP1A antibody
See all MYBBP1A primary antibodies -
Description
Mouse polyclonal to MYBBP1A -
Host species
Mouse -
Tested applications
Suitable for: WB, ICC/IFmore details -
Species reactivity
Reacts with: Human -
Immunogen
Recombinant full length protein within Human MYBBP1A. The exact immunogen sequence used to generate this antibody is proprietary information. If additional detail on the immunogen is needed to determine the suitability of the antibody for your needs, please contact our Scientific Support team to discuss your requirements.
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Positive control
- WB: 293 cell lysate; ICC/IF: Hela cells.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
Storage buffer
pH: 7.40
Constituent: 100% PBS -
Concentration information loading...
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Purity
Protein A purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab89121 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
Use a concentration of 1 µg/ml. Predicted molecular weight: 149 kDa.
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ICC/IF |
Use a concentration of 10 µg/ml.
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Notes |
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WB
Use a concentration of 1 µg/ml. Predicted molecular weight: 149 kDa. |
ICC/IF
Use a concentration of 10 µg/ml. |
Target
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Function
May activate or repress transcription via interactions with sequence specific DNA-binding proteins. Repression may be mediated at least in part by histone deacetylase activity (HDAC activity). -
Cellular localization
Cytoplasm. Nucleus. Nucleus > nucleolus. Shuttles between the nucleus and cytoplasm. Nuclear import may be mediated by KPNA2, while export appears to depend partially on XPO1/CRM1 (By similarity). Predominantly nucleolar. - Information by UniProt
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Database links
- Entrez Gene: 10514 Human
- Omim: 604885 Human
- SwissProt: Q9BQG0 Human
- Unigene: 701718 Human
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Alternative names
- AL024407 antibody
- AU019902 antibody
- cb486 antibody
see all
Images
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Anti-MYBBP1A antibody (ab89121) at 1 µg/ml + 293 cell lysate at 50 µg
Predicted band size: 149 kDa -
All lanes : Anti-MYBBP1A antibody (ab89121) at 1 µg/ml
Lane 1 : MYBBP1A-transfected 293T cell lysate
Lane 2 : Non transfected lysate
Lysates/proteins at 25 µg per lane.
Predicted band size: 149 kDa -
ab89121, at 10 µg/ml, staining MYBBP1A in Hela cell by Immunofluorescence.
Protocols
Datasheets and documents
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Datasheet download
References (2)
ab89121 has been referenced in 2 publications.
- Felipe-Abrio B et al. Loss of MYBBP1A Induces Cancer Stem Cell Activity in Renal Cancer. Cancers (Basel) 11:N/A (2019). PubMed: 30781655
- Marin-Vicente C et al. RRP6/EXOSC10 is required for the repair of DNA double-strand breaks by homologous recombination. J Cell Sci 128:1097-107 (2015). PubMed: 25632158