Anti-Mycobacterium tuberculosis antibody (ab905)


  • Product name
    Anti-Mycobacterium tuberculosis antibody
    See all Mycobacterium tuberculosis primary antibodies
  • Description
    Rabbit polyclonal to Mycobacterium tuberculosis
  • Host species
  • Specificity
    This antibody is reactive with other Mycobacteria species including: M. avium, M. phlei, and M. parafortuitum. This antibody has been reported not to be reactive with E. coli K12, Salmonella typhimurium, Pseudomonas aeruginosa, Streptococcus (group B), Candida albicans and Neisseria meningitides.
  • Tested applications
    Suitable for: ICC/IF, IHC-P, IHC-Frmore details
  • Species reactivity
  • Immunogen

    Purified Protein Derivative

  • Positive control
    • Infected lung


  • Form
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage buffer
    Preservative: 0.1% Sodium Azide
    Constituents: PBS, Carrier protein, Da Vinci Green Diluent, pH 7.3
  • Concentration information loading...
  • Purity
    IgG fraction
  • Clonality
  • Isotype
  • Research areas


Our Abpromise guarantee covers the use of ab905 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use at an assay dependent concentration. PubMed: 24475192
IHC-P 1/100 - 1/200. Perform enzymatic antigen retrieval before commencing with IHC staining protocol. ABC method.
IHC-Fr 1/100 - 1/200.

ABC method.


  • Relevance
    Mycobacterium tuberculosis is the most common cause of tuberculosis. Primary infection begins with inhalation of 1 to 10 aerosolised bacilli. The pathogenicity of the organism is determined by its ability to escape host immune responses as well as eliciting delayed hypersensitivity. Alveolar macrophages engulf the invading cells but are unable to mount an effective defense. Several virulence factors are responsible for this apparent failure; most notably in the mycobacterial cell wall are the cord factor, lipoarabinomannan, and the 65 kd heat shock protein or HSP65. The emergence of new strains of resistant Mycobacterium tuberculosis has created new interest in clinical diagnosis. Studies have shown immunohistochemical techniques to be superior to conventional special stains. Thus the demonstration of mycobacterial antigens are not only useful in establishing mycobacterial aetiology, but can also be used as an alternative method to the conventional Ziehl-Neelsen method.
  • Alternative names
    • M. tuberculosis antibody


  • Lung tissue stained with ab905 at 1/500.


This product has been referenced in:
  • Parasa VR  et al. Evaluation of the immunogenic capability of the BCG strains BCG?BCG1419c and BCG?BCG1416c in a three-dimensional human lung tissue model. Vaccine 36:1811-1815 (2018). Read more (PubMed: 29475763) »
  • Kayanuma H  et al. Disseminated nontuberculous mycobacterial disease in a cat caused by Mycobacterium sp. strain MFM001. Vet Microbiol 220:90-96 (2018). Read more (PubMed: 29885807) »

See all 10 Publications for this product

Customer reviews and Q&As

Thank you for your enquiry.

I am sorry to confirm that after further investigation with our source, I can confirm that ab20962 has not specifically been tested for detection of BCG.

If they would like totryit for detection of BCG,...

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Thank you for contacting us.

This is a polyclonal antibody that was produced using PPD (Purified Protein Derivative) from M. tuberculosis. PPD is a collection of soluble proteins secreted into the culture medium when M. tuberculosis is grown...

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Thank you for your inquiry.

ab905 is a polyclonal antibody that was produced using PPD (Purified Protein Derivative)from M. tuberculosis.

PPD is a collection of soluble proteins secreted into the culture medium when M. tuberculosis ...

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Thank you for your enquiry. I regret to inform you that the originator of this antibody no longer has sufficient stocks for us to be able to make this product available to our customers. We have therefore been forced to withdraw ab34957 from our pr...

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Thank you for contacting us.  I apologize for the delay in my reply.  The Mycobacterium tuberculosis antibody ab905 is also reactive with M. avium, M. phlei, and M. parafortuitum.  This antibody does not react with E. coli K12, Salmonella typhimuri...

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Thank you for your enquiry. Unfortunately we have no information as to whether the antibody cross-reacts with that strain. I am sorry I could not be more helpful. Please do not hesitate to contact us if you need anything further.

Abcam guarantees this product to work in the species/application used in this Abreview.
Immunohistochemistry (Frozen sections)
Human Tissue sections (Inflamed synovium from patients (osteoarthritis))
Inflamed synovium from patients (osteoarthritis)
Blocking step
Serum as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 0.05% BSA

Dr. Dan McWilliams

Verified customer

Submitted Nov 28 2005

Thank you for explaining your details to me. I now understand why you would choose to use a anti-TB antibody on mammalian cells. Following your comprehensive experiments it appears that there is clear reactivity against a human target protein by th...

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Thank you for your enquiry. We do not routinely offer free or trial sized samples for testing purposes. Our policy at Abcam is that if an antibody does not work as specified on the datasheet, we will offer a replacement or reimbursement. Should you...

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