Biotin Anti-Mycobacterium tuberculosis antibody (ab20027)
Key features and details
- Biotin Rabbit polyclonal to Mycobacterium tuberculosis
- Suitable for: IHC-P
- Conjugation: Biotin
- Isotype: IgG
Overview
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Product name
Biotin Anti-Mycobacterium tuberculosis antibody
See all Mycobacterium tuberculosis primary antibodies -
Description
Biotin Rabbit polyclonal to Mycobacterium tuberculosis -
Host species
Rabbit -
Conjugation
Biotin -
Specificity
Minimum of two major M. tuberculosis bands by immunoelectrophoresis (gamma & beta). -
Tested applications
Suitable for: IHC-Pmore details -
Species reactivity
Reacts with: Mycobacterium tuberculosis -
Immunogen
Full length native protein (purified) corresponding to Mycobacterium tuberculosis. Purified Protein Derivative (used for Tb skin testing)
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
Preservative: 0.1% Sodium azide
Constituent: 0.0268% PBS -
Concentration information loading...
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Purity
Protein G purified -
Purification notes
IgG fraction covalently coupled with the N-Hydroxysuccinimide ester of biotin under mild conditions to give a high degree of substitution. -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab20027 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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IHC-P |
Use at an assay dependent dilution. Do not perform antigen retrieval.
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Notes |
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IHC-P
Use at an assay dependent dilution. Do not perform antigen retrieval. |
Target
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Relevance
Mycobacterium tuberculosis is the most common cause of tuberculosis. Primary infection begins with inhalation of 1 to 10 aerosolised bacilli. The pathogenicity of the organism is determined by its ability to escape host immune responses as well as eliciting delayed hypersensitivity. Alveolar macrophages engulf the invading cells but are unable to mount an effective defense. Several virulence factors are responsible for this apparent failure; most notably in the mycobacterial cell wall are the cord factor, lipoarabinomannan, and the 65 kd heat shock protein or HSP65. The emergence of new strains of resistant Mycobacterium tuberculosis has created new interest in clinical diagnosis. Studies have shown immunohistochemical techniques to be superior to conventional special stains. Thus the demonstration of mycobacterial antigens are not only useful in establishing mycobacterial aetiology, but can also be used as an alternative method to the conventional Ziehl-Neelsen method. -
Alternative names
- M. tuberculosis antibody
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab20027 has not yet been referenced specifically in any publications.