Mycophenolate mofetil, MPDH inhibitor (ab143013)
Overview
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Product name
Mycophenolate mofetil, MPDH inhibitor -
Description
Selective, non-competitive and reversible IMPDH inhibitor. Immunosuppressant agent. -
Biological description
Selective, non-competitive and reversible IMPDH inhibitor (IC50 = 3 μM). Immunosuppressant agent. Inhibits guanosine synthesis. Shows antiparasitic effects and suppresses T cells and B cells in vivo. Orally active. -
Purity
> 99% -
CAS Number
128794-94-5 -
Chemical structure
Properties
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Chemical name
2-Morpholin-4-ylethyl (E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1H-2-benzofuran-5-yl)-4-methylhex-4-enoate -
Molecular weight
433.49 -
Molecular formula
C23H31NO7 -
PubChem identifier
5281078 -
Storage instructions
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
C12=C(C(=C(C(=C1O)C/C=C(/CCC(OCCN3CCOCC3)=O)C)OC)C)COC2=O -
Source
Synthetic
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Research areas
- Epigenetics and Nuclear Signaling
- Nuclear Signaling Pathways
- Nuclear Receptors
- Orphan Nuclear Receptors
- Metabolism
- Pathways and Processes
- Metabolic signaling pathways
- Nucleotide metabolism
- Molecular processes
- Mitochondrial transcription
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
References (0)
ab143013 has not yet been referenced specifically in any publications.
