Overview

  • Product name

    Mycophenolate mofetil, MPDH inhibitor
  • Description

    Selective, non-competitive and reversible IMPDH inhibitor. Immunosuppressant agent.
  • Biological description

    Selective, non-competitive and reversible IMPDH inhibitor (IC50 = 3 μM). Immunosuppressant agent. Inhibits guanosine synthesis. Shows antiparasitic effects and suppresses T cells and B cells in vivo. Orally active.
  • Purity

    > 99%
  • CAS Number

    128794-94-5
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Cao S  et al. Mycophenolic Acid, Mycophenolate Mofetil, Mizoribine, Ribavirin, and 7-Nitroindole Inhibit Propagation of Babesia Parasites by Targeting Inosine 5'-Monophosphate Dehydrogenase. J Parasitol : (2014). Read more (PubMed: 24580148) »
  • Wang Y  et al. Calcineurin Inhibitors Stimulate and Mycophenolic Acid Inhibits Replication of Hepatitis E Virus. Gastroenterology : (2014). Read more (PubMed: 24582714) »
  • Allison AC & Eugui EM Mycophenolate mofetil and its mechanisms of action. Immunopharmacology 47:85-118 (2000). Read more (PubMed: 10878285) »

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