Mycophenolic acid, Inosine monophosphate dehydrogenase inhibitor. (ab120664)
Key features and details
- Immunosuppressant. Inosine monophosphate dehydrogenase inhibitor.
- CAS Number: 24280-93-1
- Purity: > 99%
- Soluble in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Mycophenolic acid, Inosine monophosphate dehydrogenase inhibitor. -
Description
Immunosuppressant. Inosine monophosphate dehydrogenase inhibitor. -
Biological description
Potent inosine monophosphate dehydrogenase inhibitor (IMPDH) (Ki values are 11 and 6 nM at IMPDH type I and II, respectively). Decreases RNA and DNA synthesis. Immunosuppressive agent. Shows antiviral and antitumor effects in vitro and in vivo.
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Purity
> 99% -
CAS Number
24280-93-1 -
Chemical structure
Properties
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Chemical name
(4E)-6-(1,3-dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-4-hexenoic acid -
Molecular weight
320.34 -
Molecular formula
C17H20O6 -
Storage instructions
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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Source
Synthetic
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Research areas
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
References (0)
ab120664 has not yet been referenced specifically in any publications.