Key features and details
- Rabbit polyclonal to MYCT1
- Suitable for: WB
- Reacts with: Mouse, Rat, Human
- Isotype: IgG
Product nameAnti-MYCT1 antibody
DescriptionRabbit polyclonal to MYCT1
Specificityab139945 will detect both isoforms of MYCT1
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Mouse, Rat, Human
A 17 amino acid synthetic peptide near the C-terminal of Human MYCT1 (NP_079383).
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
Storage bufferpH: 7.2
Preservative: 0.02% Sodium azide
Constituent: 99% PBS
Concentration information loading...
PurityImmunogen affinity purified
Purification notesAffinity chromatography purified via peptide column.
Immunizing Peptide (Blocking)
Our Abpromise guarantee covers the use of ab139945 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 27 kDa.Can be blocked with MYCT1 peptide (ab177286).|
FunctionMay regulate certain MYC target genes, MYC seems to be a direct upstream transcriptional activator. Does not seem to significantly affect growth cell capacity. Overexpression seems to mediate many of the known phenotypic features associated with MYC, including promotion of apoptosis, alteration of morphology, enhancement of anchorage-independent growth, tumorigenic conversion, promotion of genomic instability, and inhibition of hematopoietic differentiation.
Tissue specificityDown-regulated in gastric cancer tissues.
Sequence similaritiesBelongs to the MYCT1 family.
Cellular localizationNucleus. Expressed in nuclei of hepatocellular carcinoma cell line Bel7402 cells.
- Information by UniProt
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ab139945 has been referenced in 1 publication.
- Zhang ZX et al. CREB promotes laryngeal cancer cell migration via MYCT1/NAT10 axis. Onco Targets Ther 11:1323-1331 (2018). PubMed: 29563811