Product nameMYCT1 peptide
Our Abpromise guarantee covers the use of ab177286 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Blocking - Blocking peptide for Anti-MYCT1 antibody (ab139945)
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Store at -20°C.
FunctionMay regulate certain MYC target genes, MYC seems to be a direct upstream transcriptional activator. Does not seem to significantly affect growth cell capacity. Overexpression seems to mediate many of the known phenotypic features associated with MYC, including promotion of apoptosis, alteration of morphology, enhancement of anchorage-independent growth, tumorigenic conversion, promotion of genomic instability, and inhibition of hematopoietic differentiation.
Tissue specificityDown-regulated in gastric cancer tissues.
Sequence similaritiesBelongs to the MYCT1 family.
Cellular localizationNucleus. Expressed in nuclei of hepatocellular carcinoma cell line Bel7402 cells.
- Information by UniProt
ab177286 has not yet been referenced specifically in any publications.