Anti-Myelin oligodendrocyte glycoprotein antibody (ab28766)

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Western blot - Anti-Myelin oligodendrocyte glycoprotein antibody (ab28766)

    Key features and details

    • Goat polyclonal to Myelin oligodendrocyte glycoprotein
    • Suitable for: WB
    • Reacts with: Human
    • Isotype: IgG

    Overview

    • Product name

      Anti-Myelin oligodendrocyte glycoprotein antibody
      See all Myelin oligodendrocyte glycoprotein primary antibodies

    • Description

      Goat polyclonal to Myelin oligodendrocyte glycoprotein

    • Host species

      Goat

    • Specificity

      This antibody is expected to recognise NP_002424 (isf 1), NP_996532 (isf a1), NP_001008229 (isf a3), NP_996535 (isf a2).

    • Tested Applications & Species

      Application Species
      WB
      Human
      See all applications and species data

    • Immunogen

      Synthetic peptide:

      (C)AGQFLEELRNPF

      , corresponding to C terminal amino acids 236-247 of Human Myelin oligodendrocyte glycoprotein
      Run BLAST with BLAST the sequence with ExPASy Run BLAST with BLAST the sequence with NCBI

    • General notes

      The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing the problem with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation.

      One factor contributing to the crisis is the use of antibodies that are not suitable. This can lead to misleading results and the use of incorrect data informing project assumptions and direction. To help address this challenge, we have introduced an application and species grid on our primary antibody datasheets to make it easy to simplify identification of the right antibody for your needs.

      Learn more here.

    Properties

    Applications

    The Abpromise guarantee

    Our Abpromise guarantee covers the use of ab28766 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Guaranteed

    Tested applications are guaranteed to work and covered by our Abpromise guarantee.

    Predicted

    Predicted to work for this combination of applications and species but not guaranteed.

    Incompatible

    Does not work for this combination of applications and species.

    Application Species
    WB
    Human
    All applications
    Mouse
    Cow
    Application Abreviews Notes
    WB
    Use a concentration of 0.03 - 1 µg/ml. Predicted molecular weight: 26 kDa.

    A 1 hour primary incubation is recommended for this product.
    Notes
    WB
    Use a concentration of 0.03 - 1 µg/ml. Predicted molecular weight: 26 kDa.

    A 1 hour primary incubation is recommended for this product.

    Target

    • Function

      Mediates homophilic cell-cell adhesion (By similarity). Minor component of the myelin sheath. May be involved in completion and/or maintenance of the myelin sheath and in cell-cell communication.

    • Tissue specificity

      Found exclusively in the CNS, where it is localized on the surface of myelin and oligodendrocyte cytoplasmic membranes.

    • Sequence similarities

      Belongs to the immunoglobulin superfamily. BTN/MOG family.
      Contains 1 Ig-like V-type (immunoglobulin-like) domain.

    • Cellular localization

      Cell membrane.
    • Information by UniProt

    • Database links

      see all

    • Alternative names

      • BTN6 antibody
      • BTNL11 antibody
      • MGC26137 antibody
      • MOG alpha 5 antibody
      • MOG alpha 6 antibody
      • MOG AluA antibody
      • MOG AluB antibody
      • MOG antibody
      • MOG Ig AluB antibody
      • MOG_HUMAN antibody
      • MOGIG2 antibody
      • Myelin oligodendrocyte glycoprotein antibody
      • Myelin-oligodendrocyte glycoprotein antibody
      • NRCLP7 antibody
      see all

    Images

    • Western blot - Anti-Myelin oligodendrocyte glycoprotein antibody (ab28766)
      Western blot - Anti-Myelin oligodendrocyte glycoprotein antibody (ab28766)
      Anti-Myelin oligodendrocyte glycoprotein antibody (ab28766) at 0.03 µg/ml + Human Brain lysate (RIPA buffer, 30µg total protein per lane).

      Predicted band size: 26 kDa



      Primary incubated for 1 hour. Detected by western blot using chemiluminescence.

    References (1)

    Publishing research using ab28766? Please let us know so that we can cite the reference in this datasheet.

    ab28766 has been referenced in 1 publication.

    • Durham-Lee JC  et al. Amiloride improves locomotor recovery after spinal cord injury. J Neurotrauma 28:1319-26 (2011). WB ; Rat . PubMed: 21534729

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