Anti-Myelin oligodendrocyte glycoprotein antibody (ab28766)
- Datasheet
- References (1)
- Protocols
Overview
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Product name
Anti-Myelin oligodendrocyte glycoprotein antibody
See all Myelin oligodendrocyte glycoprotein primary antibodies -
Description
Goat polyclonal to Myelin oligodendrocyte glycoprotein -
Host species
Goat -
Specificity
This antibody is expected to recognise NP_002424 (isf 1), NP_996532 (isf a1), NP_001008229 (isf a3), NP_996535 (isf a2). -
Tested applications
Suitable for: ELISA, WBmore details -
Species reactivity
Reacts with: Rat, Human
Predicted to work with: Mouse, Cow
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Immunogen
Synthetic peptide:
(C)AGQFLEELRNPF
, corresponding to C terminal amino acids 236-247 of Human Myelin oligodendrocyte glycoprotein
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
Storage buffer
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 0.5% Tris, 0.5% BSA -
Concentration information loading... -
Purity
Immunogen affinity purified -
Purification notes
This antibody was purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
Our Abpromise guarantee covers the use of ab28766 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| ELISA | ||
| WB |
Application notes
Peptide ELISA: 1/16000.
WB: Use at a concentration of 0.03 - 1 µg/ml. Predicted molecular weight: 26 kDa.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
WB: Use at a concentration of 0.03 - 1 µg/ml. Predicted molecular weight: 26 kDa.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
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Function
Mediates homophilic cell-cell adhesion (By similarity). Minor component of the myelin sheath. May be involved in completion and/or maintenance of the myelin sheath and in cell-cell communication. -
Tissue specificity
Found exclusively in the CNS, where it is localized on the surface of myelin and oligodendrocyte cytoplasmic membranes. -
Sequence similarities
Belongs to the immunoglobulin superfamily. BTN/MOG family.
Contains 1 Ig-like V-type (immunoglobulin-like) domain. -
Cellular localization
Cell membrane. - Information by UniProt
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Database links
- Entrez Gene: 280863 Cow
- Entrez Gene: 4340 Human
- Entrez Gene: 17441 Mouse
- Entrez Gene: 24558 Rat
- Omim: 159465 Human
- SwissProt: P55803 Cow
- SwissProt: Q16653 Human
- SwissProt: Q61885 Mouse
see all -
Alternative names
- BTN6 antibody
- BTNL11 antibody
- MGC26137 antibody
see all
Images
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Western blot - Anti-Myelin oligodendrocyte glycoprotein antibody (ab28766)Anti-Myelin oligodendrocyte glycoprotein antibody (ab28766) at 0.03 µg/ml + Human Brain lysate (RIPA buffer, 30µg total protein per lane).
Predicted band size: 26 kDa
Primary incubated for 1 hour. Detected by western blot using chemiluminescence.
Protocols
Datasheets and documents
References
This product has been referenced in:
- Durham-Lee JC et al. Amiloride improves locomotor recovery after spinal cord injury. J Neurotrauma 28:1319-26 (2011). WB ; Rat . Read more (PubMed: 21534729) »
