Anti-Myelin oligodendrocyte glycoprotein antibody (ab28766)
- Datasheet
- References (1)
- Protocols
Overview
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Product nameAnti-Myelin oligodendrocyte glycoprotein antibody
See all Myelin oligodendrocyte glycoprotein primary antibodies -
DescriptionGoat polyclonal to Myelin oligodendrocyte glycoprotein
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Host speciesGoat
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SpecificityThis antibody is expected to recognise NP_002424 (isf 1), NP_996532 (isf a1), NP_001008229 (isf a3), NP_996535 (isf a2).
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Tested applicationsSuitable for: ELISA, WBmore details
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Species reactivityReacts with: Rat, Human
Predicted to work with: Mouse, Cow
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Immunogen
Synthetic peptide:
(C)AGQFLEELRNPF
, corresponding to C terminal amino acids 236-247 of Human Myelin oligodendrocyte glycoprotein
Properties
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FormLiquid
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Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
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Storage bufferPreservative: 0.02% Sodium Azide
Constituents: 0.5% BSA, 5mg/ml Tris, pH 7.3 -
Concentration information loading... -
PurityImmunogen affinity purified
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Purification notesThis antibody was purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
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ClonalityPolyclonal
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IsotypeIgG
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Research areas
Associated products
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Compatible Secondaries
Applications
Our Abpromise guarantee covers the use of ab28766 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| ELISA | ||
| WB |
Application notes
Peptide ELISA: 1/16000.
WB: Use at a concentration of 0.03 - 1 µg/ml. Predicted molecular weight: 26 kDa.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
WB: Use at a concentration of 0.03 - 1 µg/ml. Predicted molecular weight: 26 kDa.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
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FunctionMediates homophilic cell-cell adhesion (By similarity). Minor component of the myelin sheath. May be involved in completion and/or maintenance of the myelin sheath and in cell-cell communication.
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Tissue specificityFound exclusively in the CNS, where it is localized on the surface of myelin and oligodendrocyte cytoplasmic membranes.
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Sequence similaritiesBelongs to the immunoglobulin superfamily. BTN/MOG family.
Contains 1 Ig-like V-type (immunoglobulin-like) domain. -
Cellular localizationCell membrane.
- Information by UniProt
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Database links
- Entrez Gene: 280863 Cow
- Entrez Gene: 4340 Human
- Entrez Gene: 17441 Mouse
- Entrez Gene: 24558 Rat
- Omim: 159465 Human
- SwissProt: P55803 Cow
- SwissProt: Q16653 Human
- SwissProt: Q61885 Mouse
see all -
Alternative names
- BTN6 antibody
- BTNL11 antibody
- MGC26137 antibody
see all
Images
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Western blot - Anti-Myelin oligodendrocyte glycoprotein antibody (ab28766)Anti-Myelin oligodendrocyte glycoprotein antibody (ab28766) at 0.03 µg/ml + Human Brain lysate (RIPA buffer, 30µg total protein per lane).
Predicted band size: 26 kDa
Primary incubated for 1 hour. Detected by western blot using chemiluminescence.
Datasheets and documents
Protocols
References
This product has been referenced in:
- Durham-Lee JC et al. Amiloride improves locomotor recovery after spinal cord injury. J Neurotrauma 28:1319-26 (2011). WB ; Rat . Read more (PubMed: 21534729) »
