Anti-Myelin oligodendrocyte glycoprotein antibody (ab28766)
Key features and details
- Goat polyclonal to Myelin oligodendrocyte glycoprotein
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-Myelin oligodendrocyte glycoprotein antibody
See all Myelin oligodendrocyte glycoprotein primary antibodies -
Description
Goat polyclonal to Myelin oligodendrocyte glycoprotein -
Host species
Goat -
Specificity
This antibody is expected to recognise NP_002424 (isf 1), NP_996532 (isf a1), NP_001008229 (isf a3), NP_996535 (isf a2). -
Tested Applications & Species
Application Species WB Human -
Immunogen
Synthetic peptide:
(C)AGQFLEELRNPF
, corresponding to C terminal amino acids 236-247 of Human Myelin oligodendrocyte glycoprotein -
General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing the problem with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation.
One factor contributing to the crisis is the use of antibodies that are not suitable. This can lead to misleading results and the use of incorrect data informing project assumptions and direction. To help address this challenge, we have introduced an application and species grid on our primary antibody datasheets to make it easy to simplify identification of the right antibody for your needs.
Learn more here.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
Storage buffer
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 0.5% Tris, 0.5% BSA -
Concentration information loading...
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Purity
Immunogen affinity purified -
Purification notes
This antibody was purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab28766 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Tested applications are guaranteed to work and covered by our Abpromise guarantee.
Predicted to work for this combination of applications and species but not guaranteed.
Does not work for this combination of applications and species.
Application | Species |
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WB |
Human
|
All applications |
Mouse
Cow
|
Application | Abreviews | Notes |
---|---|---|
WB |
Use a concentration of 0.03 - 1 µg/ml. Predicted molecular weight: 26 kDa.
A 1 hour primary incubation is recommended for this product. |
Notes |
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WB
Use a concentration of 0.03 - 1 µg/ml. Predicted molecular weight: 26 kDa. A 1 hour primary incubation is recommended for this product. |
Target
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Function
Mediates homophilic cell-cell adhesion (By similarity). Minor component of the myelin sheath. May be involved in completion and/or maintenance of the myelin sheath and in cell-cell communication. -
Tissue specificity
Found exclusively in the CNS, where it is localized on the surface of myelin and oligodendrocyte cytoplasmic membranes. -
Sequence similarities
Belongs to the immunoglobulin superfamily. BTN/MOG family.
Contains 1 Ig-like V-type (immunoglobulin-like) domain. -
Cellular localization
Cell membrane. - Information by UniProt
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Database links
- Entrez Gene: 280863 Cow
- Entrez Gene: 4340 Human
- Entrez Gene: 17441 Mouse
- Omim: 159465 Human
- SwissProt: P55803 Cow
- SwissProt: Q16653 Human
- SwissProt: Q61885 Mouse
- Unigene: 141308 Human
see all -
Alternative names
- BTN6 antibody
- BTNL11 antibody
- MGC26137 antibody
see all
Images
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Anti-Myelin oligodendrocyte glycoprotein antibody (ab28766) at 0.03 µg/ml + Human Brain lysate (RIPA buffer, 30µg total protein per lane).
Predicted band size: 26 kDa
Primary incubated for 1 hour. Detected by western blot using chemiluminescence.
Datasheets and documents
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SDS download
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Datasheet download
References (1)
ab28766 has been referenced in 1 publication.
- Durham-Lee JC et al. Amiloride improves locomotor recovery after spinal cord injury. J Neurotrauma 28:1319-26 (2011). WB ; Rat . PubMed: 21534729