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Neuroscience Cell Type Marker Glia marker Oligodendrocyte marker
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Anti-Myelin oligodendrocyte glycoprotein antibody [CL2852] (ab243034)

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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Myelin oligodendrocyte glycoprotein antibody [CL2852] (ab243034)
  • Western blot - Anti-Myelin oligodendrocyte glycoprotein antibody [CL2852] (ab243034)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Myelin oligodendrocyte glycoprotein antibody [CL2852] (ab243034)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Myelin oligodendrocyte glycoprotein antibody [CL2852] (ab243034)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Myelin oligodendrocyte glycoprotein antibody [CL2852] (ab243034)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Myelin oligodendrocyte glycoprotein antibody [CL2852] (ab243034)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Myelin oligodendrocyte glycoprotein antibody [CL2852] (ab243034)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Myelin oligodendrocyte glycoprotein antibody [CL2852] (ab243034)

Key features and details

  • Mouse monoclonal [CL2852] to Myelin oligodendrocyte glycoprotein
  • Suitable for: IHC-P, WB
  • Reacts with: Mouse, Rat, Human
  • Isotype: IgG1

You may also be interested in

Protein
Recombinant Human Myelin oligodendrocyte glycoprotein (ab152080)
Secondary
Product image
Goat Anti-Mouse IgG H&L (HRP) (ab205719)

View more associated products

Overview

  • Product name

    Anti-Myelin oligodendrocyte glycoprotein antibody [CL2852]
    See all Myelin oligodendrocyte glycoprotein primary antibodies
  • Description

    Mouse monoclonal [CL2852] to Myelin oligodendrocyte glycoprotein
  • Host species

    Mouse
  • Tested applications

    Suitable for: IHC-P, WBmore details
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    Recombinant fragment corresponding to Human Myelin oligodendrocyte glycoprotein aa 43-155.
    Sequence:

    ALVGDEVELPCRISPGKNATGMEVGWYRPPFSRVVHLYRNGKDQDGDQAP EYRGRTELLKDAIGEGKVTLRIRNVRFSDEGGFTCFFRDHSYQEEAAMEL KVEDPFYWVSPG


    Database link: Q16653
    Run BLAST with BLAST the sequence with ExPASy Run BLAST with BLAST the sequence with NCBI
  • Positive control

    • IHC-P: Rat cerebellum, mouse cerebellum, human cerebral cortex, rat striatum, mouse corpus callosum and human cerebellum tissues. WB: Human cerebral cortex tissue lysate.
  • General notes

    Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.

    Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.

    We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.

    In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.

    We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.

    Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.

    Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    pH: 7.20
    Preservative: 0.02% Sodium azide
    Constituents: 40% Glycerol, PBS
  • Concentration information loading...
  • Purity

    Protein A purified
  • Clonality

    Monoclonal
  • Clone number

    CL2852
  • Isotype

    IgG1
  • Research areas

    • Neuroscience
    • Cell Type Marker
    • Glia marker
    • Oligodendrocyte marker
    • Neuroscience
    • Neurology process
    • Neurogenesis
    • Neuroscience
    • Cell Type Marker
    • Neuron marker
    • Axon marker
    • Neuroscience
    • Neurology process
    • Neuroregeneration
    • Neuroregeneration

Associated products

  • Compatible Secondaries

    • Goat Anti-Mouse IgG H&L (Alexa Fluor® 488) (ab150113)
    • Goat Anti-Mouse IgG H&L (HRP) (ab205719)
  • Recombinant Protein

    • Recombinant Human Myelin oligodendrocyte glycoprotein (ab152080)

Applications

Our Abpromise guarantee covers the use of ab243034 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/1000 - 1/2500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
WB Use a concentration of 1 µg/ml.

Target

  • Function

    Mediates homophilic cell-cell adhesion (By similarity). Minor component of the myelin sheath. May be involved in completion and/or maintenance of the myelin sheath and in cell-cell communication.
  • Tissue specificity

    Found exclusively in the CNS, where it is localized on the surface of myelin and oligodendrocyte cytoplasmic membranes.
  • Sequence similarities

    Belongs to the immunoglobulin superfamily. BTN/MOG family.
    Contains 1 Ig-like V-type (immunoglobulin-like) domain.
  • Cellular localization

    Cell membrane.
  • Target information above from: UniProt accession Q16653 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt
  • Database links

    • Entrez Gene: 4340 Human
    • Entrez Gene: 17441 Mouse
    • Entrez Gene: 24558 Rat
    • Omim: 159465 Human
    • SwissProt: Q16653 Human
    • SwissProt: Q61885 Mouse
    • SwissProt: Q63345 Rat
    • Unigene: 141308 Human
    • Unigene: 210857 Mouse
    • Unigene: 9687 Rat
    see all
  • Alternative names

    • BTN6 antibody
    • BTNL11 antibody
    • MGC26137 antibody
    • MOG alpha 5 antibody
    • MOG alpha 6 antibody
    • MOG AluA antibody
    • MOG AluB antibody
    • MOG antibody
    • MOG Ig AluB antibody
    • MOG_HUMAN antibody
    • MOGIG2 antibody
    • Myelin oligodendrocyte glycoprotein antibody
    • Myelin-oligodendrocyte glycoprotein antibody
    • NRCLP7 antibody
    see all

Images

  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Myelin oligodendrocyte glycoprotein antibody [CL2852] (ab243034)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Myelin oligodendrocyte glycoprotein antibody [CL2852] (ab243034)

    Paraffin-embedded rat cerebellum tissue stained for oligodendrocyte glycoprotein (green) using ab243034 at 1/2500 dilution in immunohistochemical analysis.

  • Western blot - Anti-Myelin oligodendrocyte glycoprotein antibody [CL2852] (ab243034)
    Western blot - Anti-Myelin oligodendrocyte glycoprotein antibody [CL2852] (ab243034)
    Anti-Myelin oligodendrocyte glycoprotein antibody [CL2852] (ab243034) at 1 µg/ml + Human cerebral cortex tissue lysate
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Myelin oligodendrocyte glycoprotein antibody [CL2852] (ab243034)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Myelin oligodendrocyte glycoprotein antibody [CL2852] (ab243034)

    Paraffin-embedded mouse cerebellum tissue stained for oligodendrocyte glycoprotein (green) using ab243034 at 1/2500 dilution in immunohistochemical analysis.

  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Myelin oligodendrocyte glycoprotein antibody [CL2852] (ab243034)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Myelin oligodendrocyte glycoprotein antibody [CL2852] (ab243034)

    Paraffin-embedded human cerebral cortex tissue stained for oligodendrocyte glycoprotein using ab243034 at 1/2500 dilution in immunohistochemical analysis.

  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Myelin oligodendrocyte glycoprotein antibody [CL2852] (ab243034)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Myelin oligodendrocyte glycoprotein antibody [CL2852] (ab243034)

    Paraffin-embedded rat striatum tissue stained for oligodendrocyte glycoprotein (green) using ab243034 at 1/2500 dilution in immunohistochemical analysis.

  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Myelin oligodendrocyte glycoprotein antibody [CL2852] (ab243034)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Myelin oligodendrocyte glycoprotein antibody [CL2852] (ab243034)

    Paraffin-embedded mouse corpus callosum tissue stained for oligodendrocyte glycoprotein (green) using ab243034 at 1/2500 dilution in immunohistochemical analysis.

  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Myelin oligodendrocyte glycoprotein antibody [CL2852] (ab243034)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Myelin oligodendrocyte glycoprotein antibody [CL2852] (ab243034)

    Paraffin-embedded human cerebellum tissue stained for oligodendrocyte glycoprotein using ab243034 at 1/2500 dilution in immunohistochemical analysis.

  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Myelin oligodendrocyte glycoprotein antibody [CL2852] (ab243034)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Myelin oligodendrocyte glycoprotein antibody [CL2852] (ab243034)

    Negative Control:

    Paraffin-embedded human liver tissue stained for oligodendrocyte glycoprotein using ab243034 at 1/2500 dilution in immunohistochemical analysis.

Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols

Datasheets and documents

    • Datasheet
  • References (0)

    Publishing research using ab243034? Please let us know so that we can cite the reference in this datasheet.

    ab243034 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

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