Anti-Myeloperoxidase antibody [2D4] (ab90810)
- Datasheet
- References (7)
- Protocols
Overview
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Product name
Anti-Myeloperoxidase antibody [2D4]
See all Myeloperoxidase primary antibodies -
Description
Mouse monoclonal [2D4] to Myeloperoxidase -
Host species
Mouse -
Tested applications
Suitable for: IHC-Fr, Flow Cyt, ICC/IF, ELISAmore details
Unsuitable for: IHC-P or WB -
Species reactivity
Reacts with: Mouse, Rat -
Immunogen
Full length native protein (purified) corresponding to Myeloperoxidase. Antigen used is purified natural MPO from mice
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
Storage buffer
Preservative: 0.02% Sodium azide
Constituents: PBS, 0.1% BSA -
Concentration information loading...
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Purity
Protein G purified -
Purification notes
ab90810 is provided as a 0.2 µm filtered solution. -
Clonality
Monoclonal -
Clone number
2D4 -
Isotype
IgG1 -
Research areas
Associated products
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Alternative Versions
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Assay kits
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
Our Abpromise guarantee covers the use of ab90810 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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IHC-Fr | 1/50. | |
Flow Cyt | 1/50. ab170190 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.
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ICC/IF | 1/50. | |
ELISA | Use at an assay dependent concentration. |
Target
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Function
Part of the host defense system of polymorphonuclear leukocytes. It is responsible for microbicidal activity against a wide range of organisms. In the stimulated PMN, MPO catalyzes the production of hypohalous acids, primarily hypochlorous acid in physiologic situations, and other toxic intermediates that greatly enhance PMN microbicidal activity. -
Involvement in disease
Defects in MPO are the cause of myeloperoxidase deficiency (MPD) [MIM:254600]. MPD is an autosomal recessive defect that results in disseminated candidiasis. -
Sequence similarities
Belongs to the peroxidase family. XPO subfamily. -
Cellular localization
Lysosome. - Information by UniProt
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Database links
- Entrez Gene: 17523 Mouse
- Entrez Gene: 303413 Rat
- SwissProt: P11247 Mouse
- Unigene: 4668 Mouse
- Unigene: 47782 Rat
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Alternative names
- 84 kDa myeloperoxidase antibody
- 89 kDa myeloperoxidase antibody
- EC 1.11.1.7 antibody
see all
Images
Protocols
Datasheets and documents
References
This product has been referenced in:
- Wang N et al. Neutrophil extracellular traps induced by VP1 contribute to pulmonary edema during EV71 infection. Cell Death Discov 5:111 (2019). Read more (PubMed: 31285854) »
- Dang G et al. Extracellular Sphingomyelinase Rv0888 of Mycobacterium tuberculosis Contributes to Pathological Lung Injury of Mycobacterium smegmatis in Mice via Inducing Formation of Neutrophil Extracellular Traps. Front Immunol 9:677 (2018). Read more (PubMed: 29670633) »