Key features and details
- Mouse monoclonal [2D4] to Myeloperoxidase (FITC)
- Suitable for: Flow Cyt
- Reacts with: Mouse, Rat
- Conjugation: FITC. Ex: 493nm, Em: 528nm
- Isotype: IgG1
Product nameAnti-Myeloperoxidase antibody [2D4] (FITC)
See all Myeloperoxidase primary antibodies
DescriptionMouse monoclonal [2D4] to Myeloperoxidase (FITC)
ConjugationFITC. Ex: 493nm, Em: 528nm
Tested applicationsSuitable for: Flow Cytmore details
Unsuitable for: IHC-P or WB
Species reactivityReacts with: Mouse, Rat
Full length native protein (purified) corresponding to Mouse Myeloperoxidase. Purified from WEHI-3 cells.
Storage instructionsShipped at 4°C. Store at +4°C.
Storage bufferPreservative: 0.02% Sodium azide
Constituents: PBS, 1% BSA
Concentration information loading...
Purification notesab90812 is 0.2 µm filtered
Our Abpromise guarantee covers the use of ab90812 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
ab91356 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.
FunctionPart of the host defense system of polymorphonuclear leukocytes. It is responsible for microbicidal activity against a wide range of organisms. In the stimulated PMN, MPO catalyzes the production of hypohalous acids, primarily hypochlorous acid in physiologic situations, and other toxic intermediates that greatly enhance PMN microbicidal activity.
Involvement in diseaseDefects in MPO are the cause of myeloperoxidase deficiency (MPD) [MIM:254600]. MPD is an autosomal recessive defect that results in disseminated candidiasis.
Sequence similaritiesBelongs to the peroxidase family. XPO subfamily.
- Information by UniProt
- 84 kDa myeloperoxidase antibody
- 89 kDa myeloperoxidase antibody
- EC 22.214.171.124 antibody
ab90812 has been referenced in 13 publications.
- Al-Haidari AA et al. Neutrophil extracellular traps promote peritoneal metastasis of colon cancer cells. Oncotarget 10:1238-1249 (2019). PubMed: 30815227
- Hawez A et al. MiR-155 Regulates PAD4-Dependent Formation of Neutrophil Extracellular Traps. Front Immunol 10:2462 (2019). PubMed: 31736940
- Ode Y et al. CIRP increases ICAM-1+ phenotype of neutrophils exhibiting elevated iNOS and NETs in sepsis. J Leukoc Biol 103:693-707 (2018). PubMed: 29345380
- Gavillet M et al. A key role for Rac and Pak signaling in neutrophil extracellular traps (NETs) formation defines a new potential therapeutic target. Am J Hematol 93:269-276 (2018). PubMed: 29124783
- Wang X et al. A Label-Free Quantitative Proteomic Analysis of Mouse Neutrophil Extracellular Trap Formation Induced by Streptococcus suis or Phorbol Myristate Acetate (PMA). Front Immunol 9:2615 (2018). PubMed: 30555459