Overview

  • Product name

    Anti-Myeloperoxidase antibody
    See all Myeloperoxidase primary antibodies
  • Description

    Rabbit polyclonal to Myeloperoxidase
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC - Wholemountmore details
  • Species reactivity

    Reacts with: Zebrafish
  • Immunogen

    Recombinant fragment within Zebrafish Myeloperoxidase aa 422-725 (internal sequence). The exact sequence is proprietary.
    Database link: 337514

  • Positive control

    • Zebrafish embryo.

Properties

Applications

Our Abpromise guarantee covers the use of ab210563 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC - Wholemount 1/100 - 1/500.

Target

  • Function

    Part of the host defense system of polymorphonuclear leukocytes. It is responsible for microbicidal activity against a wide range of organisms. In the stimulated PMN, MPO catalyzes the production of hypohalous acids, primarily hypochlorous acid in physiologic situations, and other toxic intermediates that greatly enhance PMN microbicidal activity.
  • Involvement in disease

    Defects in MPO are the cause of myeloperoxidase deficiency (MPD) [MIM:254600]. MPD is an autosomal recessive defect that results in disseminated candidiasis.
  • Sequence similarities

    Belongs to the peroxidase family. XPO subfamily.
  • Cellular localization

    Lysosome.
  • Information by UniProt
  • Alternative names

    • 84 kDa myeloperoxidase antibody
    • 89 kDa myeloperoxidase antibody
    • EC 1.11.1.7 antibody
    • EC1.11.2.2 antibody
    • fj80f04 antibody
    • MPO antibody
    • mpx antibody
    • myeloid-specific peroxidase antibody
    • Myeloperoxidase antibody
    • Myeloperoxidase heavy chain antibody
    • Myeloperoxidase light chain antibody
    • PERM_HUMAN antibody
    • wu:fj80f04 antibody
    see all

Images

  • Immunohistochemical analysis of whole-mount 2-day post-fertilization zebrafish embryo, labeling Myeloperoxidase using ab210563 at a 1/100 dilution.

  • Immunohistochemical analysis of paraformaldehyde-fixed, whole-mount zebrafish embryos labeling Myeloperoxidase using ab210563 at a 1/200 dilution.

  • Immunohistochemical analysis of whole-mount 2-day post-fertilization zebrafish embryo, labeling Myeloperoxidase using ab210563 at a 1/100 dilution.

References

ab210563 has not yet been referenced specifically in any publications.

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