Anti-MYH6 antibody - N-terminal (ab228353)

Rabbit polyclonal heavy chain cardiac Myosin antibody. Validated in WB and tested in Mouse. Immunogen corresponding to synthetic peptide.

Overview

  • Product name

    Anti-MYH6 antibody - N-terminal
    See all MYH6 primary antibodies
  • Description

    Rabbit polyclonal to MYH6 - N-terminal
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Mouse
    Predicted to work with: Human
  • Immunogen

    Synthetic peptide within Human MYH6 (N terminal). The exact sequence is proprietary. Conjugated to a protein carrier.
    Database link: P12883

  • Positive control

    • WB: Mouse muscle tissue extract.

Properties

Applications

Our Abpromise guarantee covers the use of ab228353 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 223 kDa.

Target

  • Function

    Muscle contraction.
  • Involvement in disease

    Atrial septal defect 3
    Cardiomyopathy, familial hypertrophic 14
    Cardiomyopathy, dilated 1EE
    Sick sinus syndrome 3
  • Sequence similarities

    Contains 1 IQ domain.
    Contains 1 myosin head-like domain.
  • Domain

    The rodlike tail sequence is highly repetitive, showing cycles of a 28-residue repeat pattern composed of 4 heptapeptides, characteristic for alpha-helical coiled coils.
    Each myosin heavy chain can be split into 1 light meromyosin (LMM) and 1 heavy meromyosin (HMM). It can later be split further into 2 globular subfragments (S1) and 1 rod-shaped subfragment (S2).
  • Cellular localization

    Cytoplasm > myofibril. Thick filaments of the myofibrils.
  • Information by UniProt
  • Database links

  • Alternative names

    • cardiac muscle alpha isoform antibody
    • MYH6 antibody
    • MYH6_HUMAN antibody
    • MYHC antibody
    • MyHC-alpha antibody
    • MyHC-beta antibody
    • MYHCA antibody
    • MYHCB antibody
    • Myosin heavy chain 6 antibody
    • Myosin heavy chain antibody
    • Myosin heavy chain cardiac muscle alpha isoform antibody
    • Myosin heavy chain cardiac muscle beta isoform antibody
    • Myosin-6 antibody
    see all

Images

  • Anti-MYH6 antibody - N-terminal (ab228353) at 1/2000 dilution + Mouse muscle tissue extract at 50 µg

    Developed using the ECL technique.

    Predicted band size: 223 kDa



    5% SDS-PAGE

References

ab228353 has not yet been referenced specifically in any publications.

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