Overview

  • Product name

    Anti-MYO10 antibody - C-terminal
    See all MYO10 primary antibodies
  • Description

    Rabbit polyclonal to MYO10 - C-terminal
  • Host species

    Rabbit
  • Tested applications

    Suitable for: ELISA, WB, IHC-Pmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Cow
  • Immunogen

    Synthetic peptide corresponding to Human MYO10 (internal sequence). (NP_036466.2).
    Sequence:

    DAFKDSPNPSEHGHSD


    Database link: Q9HD67

  • Positive control

    • Human skeletal muscle tissue.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    Preservative: 0.01% Sodium azide
    Constituents: 50% Glycerol, 49% PBS
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab189259 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA Use at an assay dependent concentration.
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 237 kDa.
IHC-P Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.

Target

  • Function

    Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments (By similarity). Plays a role in regions of dynamic actin.
  • Sequence similarities

    Contains 1 FERM domain.
    Contains 3 IQ domains.
    Contains 1 myosin head-like domain.
    Contains 1 MyTH4 domain.
    Contains 2 PH domains.
  • Information by UniProt
  • Database links

  • Alternative names

    • AW048724 antibody
    • D15Ertd600e antibody
    • FLJ10639 antibody
    • FLJ21066 antibody
    • FLJ22268 antibody
    • FLJ43256 antibody
    • KIAA0799 antibody
    • MGC131988 antibody
    • mKIAA0799 antibody
    • MYO10 antibody
    • MYO10_HUMAN antibody
    • Myosin X antibody
    • Myosin-X antibody
    • OTTMUSP00000022066 antibody
    • Unconventional myosin 10 antibody
    • Unconventional myosin X antibody
    • Unconventional myosin-10 antibody
    see all

Images

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human skeletal muscle tissue labeling MYO10 with ab189259 at 5 µg/ml.

References

This product has been referenced in:

  • Wang X  et al. miR-129 inhibits tumor growth and potentiates chemosensitivity of neuroblastoma by targeting MYO10. Biomed Pharmacother 103:1312-1318 (2018). IHC-P ; Human . Read more (PubMed: 29864913) »
  • Sun Y  et al. NF-?B-mediated miR-124 suppresses metastasis of non-small-cell lung cancer by targeting MYO10. Oncotarget 6:8244-54 (2015). WB . Read more (PubMed: 25749519) »
See all 2 Publications for this product

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab189259.
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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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