Key features and details
- Rabbit polyclonal to MYO5B
- Suitable for: WB, ELISA
- Reacts with: Recombinant fragment
- Isotype: IgG
Product nameAnti-MYO5B antibody
See all MYO5B primary antibodies
DescriptionRabbit polyclonal to MYO5B
Tested applicationsSuitable for: WB, ELISAmore details
Species reactivityReacts with: Recombinant fragment
Predicted to work with: Mouse
Synthetic peptide corresponding to C-terminal residues of human MYO5B
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage bufferPreservative: 0.01% Sodium azide
Constituents: PBS, 50% Glycerol
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab58765 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||Use a concentration of 1 µg/ml. Predicted molecular weight: 214 kDa. This antibody has been tested in Western blot against the recombinant peptide used as an immunogen. We have no data on detection of endogenous protein.|
|ELISA||Use at an assay dependent dilution.|
FunctionMay be involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation. Required in a complex with RAB11A and RAB11FIP2 for the transport of NPC1L1 to the plasma membrane. Together with RAB11A participates in CFTR trafficking to the plasma membrane and TF (transferrin) recycling in nonpolarized cells. Together with RAB11A and RAB8A participates in epithelial cell polarization. Together with RAB25 regulates transcytosis.
Involvement in diseaseDiarrhea 2, with microvillus atrophy
Sequence similaritiesContains 1 dilute domain.
Contains 6 IQ domains.
Contains 1 myosin head-like domain.
- Information by UniProt
- KIAA1119 antibody
- Myo5b antibody
- MYO5B_HUMAN antibody
ab58765 has been referenced in 1 publication.
- Gao N & Kaestner KH Cdx2 regulates endo-lysosomal function and epithelial cell polarity. Genes Dev 24:1295-305 (2010). WB ; Mouse . PubMed: 20551175