Anti-MYO5B antibody - N-terminal (ab190096)
Key features and details
- Rabbit polyclonal to MYO5B - N-terminal
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-MYO5B antibody - N-terminal
See all MYO5B primary antibodies -
Description
Rabbit polyclonal to MYO5B - N-terminal -
Host species
Rabbit -
Tested applications
Suitable for: IHC-Pmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse -
Immunogen
Synthetic peptide within Human MYO5B (N terminal). The exact sequence is proprietary. (NM_001080467)
Database link: Q9ULV0 -
Positive control
- Human skeletal muscle
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.20
Preservative: 0.09% Sodium azide
Constituents: 49% PBS, 50% Glycerol -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab190096 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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IHC-P |
Use a concentration of 2.5 - 5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
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Notes |
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IHC-P
Use a concentration of 2.5 - 5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
Target
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Function
May be involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation. Required in a complex with RAB11A and RAB11FIP2 for the transport of NPC1L1 to the plasma membrane. Together with RAB11A participates in CFTR trafficking to the plasma membrane and TF (transferrin) recycling in nonpolarized cells. Together with RAB11A and RAB8A participates in epithelial cell polarization. Together with RAB25 regulates transcytosis. -
Involvement in disease
Diarrhea 2, with microvillus atrophy -
Sequence similarities
Contains 1 dilute domain.
Contains 6 IQ domains.
Contains 1 myosin head-like domain. - Information by UniProt
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Database links
- Entrez Gene: 4645 Human
- SwissProt: Q9ULV0 Human
- SwissProt: P21271 Mouse
- Unigene: 720076 Human
- Unigene: 260098 Mouse
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Alternative names
- KIAA1119 antibody
- Myo5b antibody
- MYO5B_HUMAN antibody
see all
Images
Datasheets and documents
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SDS download
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Datasheet download
References (1)
ab190096 has been referenced in 1 publication.
- Qiu YL et al. Defects in myosin VB are associated with a spectrum of previously undiagnosed low ?-glutamyltransferase cholestasis. Hepatology 65:1655-1669 (2017). PubMed: 28027573