Overview

  • Product name

    Anti-Myosin VIIa/MYO7A antibody
    See all Myosin VIIa/MYO7A primary antibodies
  • Description

    Rabbit polyclonal to Myosin VIIa/MYO7A
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-P, WBmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat, Pig
  • Immunogen

    Synthetic peptide corresponding to Human Myosin VIIa/MYO7A (internal sequence) conjugated to keyhole limpet haemocyanin.
    Database link: Q13402

  • Positive control

    • IHC-P: Human brain cortex tissue. WB: SKOVCAR and HEK-293T whole cell lysates.
  • General notes

     This product was previously labelled as Myosin VIIa

     

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    pH: 7.30
    Preservative: 0.01% Sodium azide
    Constituents: PBS, 30% Glycerol
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab230631 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/100.
WB 1/500 - 1/1000. Predicted molecular weight: 254 kDa.

Target

  • Relevance

    Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments. In retina, myosin VIIa may play a role in trafficking of ribbon-synaptic vesicle complexes and renewal of the outer photoreceptors disks. In inner ear, it may maintain the rigidity of stereocilia during the dynamic movements of the bundle.
  • Cellular localization

    Cytoplasmic, cytoskeleton
  • Database links

  • Alternative names

    • Deafness autosomal dominant 11 antibody
    • Deafness autosomal recessive 2 antibody
    • DFNA11 antibody
    • DFNB 2 antibody
    • DFNB2 antibody
    • Myo7a antibody
    • Myosin 7a antibody
    • Myosin VIIA (Usher syndrome 1B (autosomal recessive, severe)) antibody
    • Myosin VIIa antibody
    • Myosin, unconventional, family VII, member A antibody
    • MYOVIIA antibody
    • MYU7A antibody
    • NSRD 2 antibody
    • NSRD2 antibody
    • Unconventional myosin VIIa antibody
    • Ush 1B antibody
    • Ush1b antibody
    • Usher syndrome 1B antibody
    see all

Images

  • Formalin-fixed, paraffin-embedded human brain cortex tissue stained for Myosin VIIa/MYO7A using ab230631 at 1/100 dilution in immunohistochemical analysis.

  • All lanes : Anti-Myosin VIIa/MYO7A antibody (ab230631) at 1/500 dilution

    Lane 1 : SKOVCAR whole cell lysate
    Lane 2 : HEK-293T (human epithelial cell line from embryonic kidney transformed with large T antigen) whole cell lysate

    Predicted band size: 254 kDa

References

ab230631 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab230631.
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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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