Product nameAnti-Myosin VIIa/MYO7A antibody
See all Myosin VIIa/MYO7A primary antibodies
DescriptionRabbit polyclonal to Myosin VIIa/MYO7A
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Mouse
Predicted to work with: Rat, Human, Pig
Synthetic peptide corresponding to Mouse Myosin VIIa/MYO7A aa 1000-1100 conjugated to keyhole limpet haemocyanin.
(Peptide available as
- This antibody gave a positive signal in mouse testis tissue lysate.
This product was previously labelled as Myosin VIIa
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage bufferPreservative: 0.02% Sodium Azide
Constituents: 1% BSA, PBS, pH 7.4
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab92996 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||Use a concentration of 1 µg/ml. Detects a band of approximately 238 kDa (predicted molecular weight: 255 kDa).|
RelevanceMyosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments. In retina, myosin VIIa may play a role in trafficking of ribbon-synaptic vesicle complexes and renewal of the outer photoreceptors disks. In inner ear, it may maintain the rigidity of stereocilia during the dynamic movements of the bundle.
Cellular localizationCytoplasmic, cytoskeleton
- Deafness autosomal dominant 11 antibody
- Deafness autosomal recessive 2 antibody
- DFNA11 antibody
Anti-Myosin VIIa/MYO7A antibody (ab92996) at 1 µg/ml + Testis (Mouse) Tissue Lysate at 10 µg
Goat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilution
Developed using the ECL technique.
Performed under reducing conditions.
Predicted band size: 255 kDa
Observed band size: 238 kDa why is the actual band size different from the predicted?
Additional bands at: 50 kDa, 60 kDa. We are unsure as to the identity of these extra bands.
Exposure time: 12 minutes
ab92996 has not yet been referenced specifically in any publications.