Key features and details
- Rabbit polyclonal to Myozenin 1
- Suitable for: WB, IHC-P
- Reacts with: Mouse, Human
- Isotype: IgG
Product nameAnti-Myozenin 1 antibody
DescriptionRabbit polyclonal to Myozenin 1
Tested applicationsSuitable for: WB, IHC-Pmore details
Species reactivityReacts with: Mouse, Human
Predicted to work with: Pig
Fusion protein corresponding to Human Myozenin 1 aa 1-299. (BC025753).
MPLSGTPAPNKKRKSSKLIMELTGGGQESSGLNLGKKISVPRDVMLEELS LLTNRGSKMFKLRQMRVEKFIYENHPDVFSDSSMDHFQKFLPTVGGQLGT AGQGFSYSKSNGRGGSQAGGSGSAGQYGSDQQHHLGSGSGAGGTGGPAGQ AGRGGAAGTAGVGETGSGDQAGGEGKHITVFKTYISPWERAMGVDPQQKM ELGIDLLAYGAKAELPKYKSFNRTAMPYGGYEKASKRMTFQMPKFDLGPL LSEPLVLYNQNLSNRPSFNRTPIPWLSSGEPVDYNVDIGIPLDGETEEL
Database link: Q9NP98
- Mouse muscle tissue lysate; Human liver cancer tissue.
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In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.4
Preservative: 0.05% Sodium azide
Constituents: 50% Glycerol (glycerin, glycerine), 49% PBS
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab197660 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500 - 1/2000. Predicted molecular weight: 32 kDa.|
|IHC-P||1/25 - 1/100.|
FunctionMyozenins may serve as intracellular binding proteins involved in linking Z-disk proteins such as alpha-actinin, gamma-filamin, TCAP/telethonin, LDB3/ZASP and localizing calcineurin signaling to the sarcomere. Plays an important role in the modulation of calcineurin signaling. May play a role in myofibrillogenesis.
Tissue specificityExpressed primarily in skeletal muscle. Detected at lower levels in heart, prostate and pancreas.
Sequence similaritiesBelongs to the myozenin family.
Cellular localizationNucleus. Cell projection > pseudopodium. Localized to the nucleus and pseudopodia of undifferentiated cells and detected throughout the myotubes of differentiated cells. Colocalizes with ACTN2, FLNC and MYOT at the Z-lines of skeletal muscle.
- Information by UniProt
- actinin- and telethonin-binding protein antibody
- Calsarcin 2 antibody
- Calsarcin-2 antibody
ab197660 has been referenced in 1 publication.
- Papadimitriou ID et al. A "human knockout" model to investigate the influence of the a-actinin-3 protein on exercise-induced mitochondrial adaptations. Sci Rep 9:12688 (2019). PubMed: 31481717