Overview

  • Product name

  • Description

    Rabbit polyclonal to MYPN
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Recombinant fragment corresponding to Human MYPN aa 536-614 (internal sequence).
    Sequence:

    EDLSNNGSLHSANSTTNLAAIEPQPSPPHSEPPSVEQPPKPKLEGVLVNH NEPRSSSRIGLRVHFNLPEDDKGSEASSE


    Database link: Q86TC9

  • Positive control

    • Human skeletal muscle tissue.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    pH: 7.2
    Preservative: 0.02% Sodium azide
    Constituents: 59% PBS, 40% Glycerol
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab204734 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/200 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function

    Component of the sarcomere that tethers together nebulin (skeletal muscle) and nebulette (cardiac muscle) to alpha-actinin, at the Z lines.
  • Tissue specificity

    Expressed in adult skeletal muscle and fetal heart.
  • Sequence similarities

    Belongs to the myotilin/palladin family.
    Contains 5 Ig-like (immunoglobulin-like) domains.
  • Cellular localization

    Cytoplasm. Nucleus. Cytoplasm > myofibril > sarcomere. Bound to sarcomere both at the Z-line periphery and in the central I-band region.
  • Information by UniProt
  • Database links

  • Alternative names

    • 145 kDa sarcomeric protein antibody
    • MYOP antibody
    • Myopalladin antibody
    • MYPN antibody
    • MYPN_HUMAN antibody
    • sarcomeric protein myopalladin antibody
    see all

Images

  • Immunohistochemical analysis of paraffin-embedded Human skeletal tissue labeling MYPN with ab204734 at 1/200 dilution.

References

ab204734 has not yet been referenced specifically in any publications.

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There are currently no Customer reviews or Questions for ab204734.
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