Overview

  • Product name

    Myristicin, Glutathione S-transferase inducer
  • Description

    Glutathione S-transferase inducer
  • Biological description

    Glutathione S-transferase inducer. Inhibits LPS-induced TNF-α release. Shows chemopreventive, potent hepatoprotective and psychoactive effects in vivo. Blood-brain barrier permeable. Orally active.
  • Purity

    > 97%
  • CAS Number

    607-91-0
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    4-Methoxy-6-prop-2-enyl-1,3-benzodioxole
  • Molecular weight

    192.21
  • Molecular formula

    C11H12O3
  • PubChem identifier

    4276
  • Storage instructions

    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in ethanol (with heating)
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    COC1=CC(=CC2=C1OCO2)CC=C
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:

  • Babu RO  et al. Virtual screening and in vitro assay of potential drug like inhibitors from spices against Glutathione-S-Transferase of Meloidogyne incognita. Bioinformation 8:319-25 (2012). Read more (PubMed: 22553389) »
  • Morita T  et al. Hepatoprotective effect of myristicin from nutmeg (Myristica fragrans) on lipopolysaccharide/d-galactosamine-induced liver injury. J Agric Food Chem 51:1560-5 (2003). Read more (PubMed: 12617584) »
  • Zheng GQ  et al. Inhibition of benzo[a]pyrene-induced tumorigenesis by myristicin, a volatile aroma constituent of parsley leaf oil. Carcinogenesis 13:1921-3 (1992). Read more (PubMed: 1423855) »

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