N-Acetyl-S-(N'-phenethylthiocarbamoyl)-L-cysteine, N-acetyl cysteine conjugate of PEITC-NAC (ab143567)

Overview

  • Product name

    N-Acetyl-S-(N'-phenethylthiocarbamoyl)-L-cysteine, N-acetyl cysteine conjugate of PEITC-NAC
  • Description

    Phenethyl isothiocyanate (PEITC) derivative
  • Biological description

    Phenethyl isothiocyanate (PEITC) derivative. PEITC induces apoptosis. Chemopreventive agent. Use in mouse lung tumor bioassays and in other models.

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  • Purity

    > 95%
  • CAS Number

    131918-97-3
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    (2R)-2-acetamido-3-(2-phenylethylcarbamothioylsulfanyl)propanoic acid
  • Molecular weight

    326.43
  • Molecular formula

    C14H18N2O3S2
  • PubChem identifier

    9797425
  • Storage instructions

    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CC(=O)N[C@@H](CSC(=S)NCCC1=CC=CC=C1)C(=O)O
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:

  • Wang Y  et al. Phenethyl isothiocyanate inhibits growth of human chronic myeloid leukemia K562 cells via reactive oxygen species generation and caspases. Mol Med Rep 10:543-9 (2014). Read more (PubMed: 24788892) »
  • Wu X  et al. Are isothiocyanates potential anti-cancer drugs? Acta Pharmacol Sin 30:501-12 (2009). Read more (PubMed: 19417730) »
  • Hecht SS Approaches to chemoprevention of lung cancer based on carcinogens in tobacco smoke. Environ Health Perspect 105 Suppl 4:955-63 (1997). Read more (PubMed: 9255587) »

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES, NOT FOR USE IN HUMANS"
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