Overview

  • Product name

    Anti-N Cadherin antibody [8C11] (Biotin)
    See all N Cadherin primary antibodies
  • Description

    Mouse monoclonal [8C11] to N Cadherin (Biotin)
  • Host species

    Mouse
  • Conjugation

    Biotin
  • Tested applications

    Suitable for: Flow Cytmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Bacterial fusion protein corresponding to the extracellular domain of Human N Cadherin.

  • Positive control

    • HeLa cells

Properties

Applications

Our Abpromise guarantee covers the use of ab93524 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt
  • Application notes
    Flow Cyt: Use 0.25µg for 105 - 108 cells in a final volume of 100µl.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function

      Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH2 may be involved in neuronal recognition mechanism. In hippocampal neurons, may regulate dendritic spine density.
    • Sequence similarities

      Contains 5 cadherin domains.
    • Cellular localization

      Cell membrane.
    • Information by UniProt
    • Database links

    • Alternative names

      • CADH2_HUMAN antibody
      • Cadherin 2 antibody
      • Cadherin 2 N cadherin neuronal antibody
      • Cadherin 2 type 1 antibody
      • Cadherin 2 type 1 N cadherin neuronal antibody
      • Cadherin 2, type 1, N-cadherin (neuronal) antibody
      • Cadherin-2 antibody
      • Cadherin2 antibody
      • Calcium dependent adhesion protein neuronal antibody
      • CD325 antibody
      • CD325 antigen antibody
      • CDH2 antibody
      • CDHN antibody
      • CDw325 antibody
      • CDw325 antigen antibody
      • N cadherin 1 antibody
      • N-cadherin antibody
      • NCAD antibody
      • Neural cadherin antibody
      • OTTHUMP00000066304 antibody
      • OTTHUMP00000067378 antibody
      see all

    Images

    • Flow Cytometry staining of Hela cell line with Biotin Mouse IgG1, K Isotype Control (blue histogram) or ab93524 (purple histogram) followed by Streptavidin PE. Total viable cells were used for analysis.

    References

    This product has been referenced in:

    • Wahl JK  et al. N-cadherin-catenin complexes form prior to cleavage of the proregion and transport to the plasma membrane. J Biol Chem 278:17269-76 (2003). WB . Read more (PubMed: 12604612) »
    • Puch S  et al. N-cadherin is developmentally regulated and functionally involved in early hematopoietic cell differentiation. J Cell Sci 114:1567-77 (2001). Flow Cyt . Read more (PubMed: 11282032) »
    See all 2 Publications for this product

    Customer reviews and Q&As

    Question
    Answer

    Si vous décidez de poursuivre vos recherches avec ab19348 et ab93524 en ICC nous vous encourageons à soumettre une Abreview via le lien situé sur notre fiche technique.

    Nous encourageons nos clients à faire partager leurs résultats, aussi bien négatifs que positifs, afin de complementer nos fiches techniques et ainsi de partager plus de données avec d'autres chercheurs.

    Découvrez notre système de soumission Abreview grâce au lien suivant :

    https://www.abcam.com/abreviews

    Notre système d'Abreviews permet aux chercheurs de soumettre leur étude de ce produit, aussi bien négative que positive. En échange, nous vous donnerons soit une remise sur votre prochain achat, ou des bons d'achats pour Amazon.fr.

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