Anti-N Cadherin antibody (ab18203)

Rabbit polyclonal N Cadherin antibody. Validated in WB, IP, IHC, Flow Cyt, ICC/IF and tested in Mouse, Rat, Human, Pig, Xenopus laevis. Cited in 153 publication(s).

Publishing research using ab18203? Please let us know so that we can cite the reference in this datasheet.

ab18203 has been referenced in 192 publications.

  • Gao J  et al. MicroRNA-590-5p functions as a tumor suppressor in breast cancer conferring inhibitory effects on cell migration, invasion, and epithelial-mesenchymal transition by downregulating the Wnt-ß-catenin signaling pathway. J Cell Physiol 234:1827-1841 (2019). PubMed: 30191949
  • Wang XH  et al. FGF represses metastasis of neuroblastoma regulated by MYCN and TGF-ß1 induced LMO1 via control of let-7 expression. Brain Res 1704:219-228 (2019). PubMed: 30321496
  • Quan R  et al. Prognostic Value of Upregulation of Myristoylated Alanine-Rich C-Kinase Substrate in Gastric Cancer. Med Sci Monit 25:279-287 (2019). PubMed: 30623893
  • Gao LM  et al. Tumor-suppressive effects of microRNA-181d-5p on non-small-cell lung cancer through the CDKN3-mediated Akt signaling pathway in vivo and in vitro. Am J Physiol Lung Cell Mol Physiol N/A:N/A (2019). PubMed: 30628487
  • Gao Y  et al. SIRT6 inhibits proliferation and invasion in osteosarcoma cells by targeting N-cadherin. Oncol Lett 17:1237-1244 (2019). PubMed: 30655890
  • Xu X  et al. The long non-coding RNA Linc-GALH promotes hepatocellular carcinoma metastasis via epigenetically regulating Gankyrin. Cell Death Dis 10:86 (2019). PubMed: 30692513
  • Tang D  et al. Inhibition of MALAT1 reduces tumor growth and metastasis and promotes drug sensitivity in colorectal cancer. Cell Signal 57:21-28 (2019). PubMed: 30716387
  • Fang Z  et al. miR-381 and miR-489 suppress cell proliferation and invasion by targeting CUL4B via the Wnt/ß-catenin pathway in gastric cancer. Int J Oncol 54:733-743 (2019). PubMed: 30483755
  • Zhang X  et al. Overexpression of E74-Like Factor 5 (ELF5) Inhibits Migration and Invasion of Ovarian Cancer Cells. Med Sci Monit 25:856-865 (2019). PubMed: 30696803
  • Feng S  et al. Tripartite motif-containing 14 (TRIM14) promotes epithelial-mesenchymal transition via ZEB2 in glioblastoma cells. J Exp Clin Cancer Res 38:57 (2019). PubMed: 30728039
  • Wang W  et al. Cathepsin L activated by mutant p53 and Egr-1 promotes ionizing radiation-induced EMT in human NSCLC. J Exp Clin Cancer Res 38:61 (2019). PubMed: 30732622
  • Lu C  et al. Coordination between TGF-ß cellular signaling and epigenetic regulation during epithelial to mesenchymal transition. Epigenetics Chromatin 12:11 (2019). PubMed: 30736855
  • Oliveira M  et al. Bone marrow mononuclear cell transplantation rescues the glomerular filtration barrier and epithelial cellular junctions in a renovascular hypertension model. Exp Physiol 104:740-754 (2019). PubMed: 30790372
  • Meng J  et al. USP5 promotes epithelial-mesenchymal transition by stabilizing SLUG in hepatocellular carcinoma. Theranostics 9:573-587 (2019). PubMed: 30809294
  • Zhang YL  et al. High Expression B3GAT3 Is Related with Poor Prognosis of Liver Cancer. Open Med (Wars) 14:251-258 (2019). PubMed: 30847403
  • Shi B  et al. MiR-106a directly targets LIMK1 to inhibit proliferation and EMT of oral carcinoma cells. Cell Mol Biol Lett 24:1 (2019). PubMed: 30873211
  • Qi M  et al. CUL4B promotes prostate cancer progression by forming positive feedback loop with SOX4. Oncogenesis 8:23 (2019). PubMed: 30872583
  • Hong X & Yu JJ Silencing of lysyl oxidase-like 2 inhibits the migration, invasion and epithelial-to-mesenchymal transition of renal cell carcinoma cells through the Src/FAK signaling pathway. Int J Oncol 54:1676-1690 (2019). PubMed: 30816490
  • Gan L  et al. Long Non-Coding RNA ZEB1-Antisense 1 Affects Cell Migration and Invasion of Cervical Cancer by Regulating Epithelial-Mesenchymal Transition via the p38MAPK Signaling Pathway. Gynecol Obstet Invest 84:136-144 (2019). PubMed: 30253398
  • Wu M  et al. LINC01433/miR-2116-3p/MYC Feedback Loop Promotes Cell Proliferation, Migration, and the Epithelial-Mesenchymal Transition in Breast Cancer. Cancer Biother Radiopharm N/A:N/A (2019). PubMed: 30939038
  • Gao K  et al. Anti-proliferation and anti-metastatic effects of sevoflurane on human osteosarcoma U2OS and Saos-2 cells. Exp Mol Pathol 108:121-130 (2019). PubMed: 30974101
  • Li Z  et al. Knockdown of lncRNA MNX1-AS1 suppresses cell proliferation, migration, and invasion in prostate cancer. FEBS Open Bio 9:851-858 (2019). PubMed: 30980513
  • Rui QH  et al. Effect of lncRNA HULC knockdown on rat secreting pituitary adenoma GH3 cells. Braz J Med Biol Res 52:e7728 (2019). PubMed: 30994730
  • Li S  et al. PTBP1 enhances exon11a skipping in Mena pre-mRNA to promote migration and invasion in lung carcinoma cells. Biochim Biophys Acta Gene Regul Mech N/A:N/A (2019). PubMed: 31075540
  • Tang L  et al. Long non-coding RNA LINC01314 represses cell migration, invasion, and angiogenesis in gastric cancer via the Wnt/ß-catenin signaling pathway by down-regulating KLK4. Cancer Cell Int 19:94 (2019). PubMed: 31007611
  • Xu XF  et al. Suppression of BMX-ARHGAP fusion gene inhibits epithelial-mesenchymal transition in gastric cancer cells via RhoA-mediated blockade of JAK/STAT axis. J Cell Biochem 120:439-451 (2019). PubMed: 30216523
  • Jiang Q  et al. Erythrocyte-cancer hybrid membrane-camouflaged melanin nanoparticles for enhancing photothermal therapy efficacy in tumors. Biomaterials 192:292-308 (2019). PubMed: 30465973
  • Yang YZ  et al. Magnesium isoglycyrrhizinate ameliorates high fructose-induced liver fibrosis in rat by increasing miR-375-3p to suppress JAK2/STAT3 pathway and TGF-ß1/Smad signaling. Acta Pharmacol Sin N/A:N/A (2018). PubMed: 30568253
  • Wang D  et al. FBXL3 is regulated by miRNA-4735-3p and suppresses cell proliferation and migration in non-small cell lung cancer. Pathol Res Pract N/A:N/A (2018). PubMed: 30594330
  • Kaowinn S  et al. STAT1-HDAC4 signaling induces epithelial-mesenchymal transition and sphere formation of cancer cells overexpressing the oncogene, CUG2. Oncol Rep 40:2619-2627 (2018). PubMed: 30226605
  • Xu GL  et al. ROR1 is highly expressed in circulating tumor cells and promotes invasion of pancreatic cancer. Mol Med Rep 18:5087-5094 (2018). PubMed: 30272313
  • Li Y  et al. Downregulation of CLDN7 due to promoter hypermethylation is associated with human clear cell renal cell carcinoma progression and poor prognosis. J Exp Clin Cancer Res 37:276 (2018). PubMed: 30428910
  • Liu B  et al. Anti-tumoral potential of MDA19 in human osteosarcoma via suppressing PI3K/Akt/mTOR signaling pathway. Biosci Rep 38:N/A (2018). PubMed: 30442873
  • Wang L  et al. MicroRNA-373 Inhibits Cell Proliferation and Invasion via Targeting BRF2 in Human Non-small Cell Lung Cancer A549 Cell Line. Cancer Res Treat 50:936-949 (2018). PubMed: 29025258
  • Lv S & Guan M miRNA-1284, a regulator of HMGB1, inhibits cell proliferation and migration in osteosarcoma. Biosci Rep 38:N/A (2018). PubMed: 29899164
  • Fan Z  et al. Bushenshugan Formula Attenuates the Development of Lung Cancer by Inhibiting Epithelial-Mesenchymal Transition. Cell Physiol Biochem 47:1977-1988 (2018). PubMed: 29969756
  • Jiang G  et al. IL-17A and GDF15 are able to induce epithelial-mesenchymal transition of lung epithelial cells in response to cigarette smoke. Exp Ther Med 16:12-20 (2018). PubMed: 29977354
  • Zhang H  et al. Loss of profilin 2 contributes to enhanced epithelial-mesenchymal transition and metastasis of colorectal cancer. Int J Oncol 53:1118-1128 (2018). PubMed: 30015842
  • Chen G  et al. Investigation of the role of cullin 4A overexpression in human liver cancer. Mol Med Rep 18:2531-2540 (2018). PubMed: 30015884
  • Chen SY  et al. MicroRNA-340 Inhibits Epithelial-Mesenchymal Transition by Impairing ROCK-1-Dependent Wnt/ß-Catenin Signaling Pathway in Epithelial Cells from Human Benign Prostatic Hyperplasia. Chin Med J (Engl) 131:2008-2012 (2018). PubMed: 30082536
  • Gao S  et al. MicroRNA-194 regulates cell viability and apoptosis by targeting CDH2 in prostatic cancer. Onco Targets Ther 11:4837-4844 (2018). PubMed: 30147335
  • Chen Y  et al. Long noncoding RNA-ATB promotes cell proliferation, migration and invasion in gastric cancer. Mol Med Rep 17:1940-1946 (2018). PubMed: 29257203
  • Lin JR  et al. Highly multiplexed immunofluorescence imaging of human tissues and tumors using t-CyCIF and conventional optical microscopes. Elife 7:N/A (2018). PubMed: 29993362
  • Wei YL  et al. LncNEN885 inhibits epithelial-mesenchymal transition by partially regulation of Wnt/ß-catenin signalling in gastroenteropancreatic neuroendocrine neoplasms. Cancer Sci 109:3139-3148 (2018). PubMed: 30033597
  • Xiong D  et al. TRIM44 promotes human esophageal cancer progression via the AKT/mTOR pathway. Cancer Sci 109:3080-3092 (2018). PubMed: 30098109
  • Chen LL  et al. SDC4 Gene Silencing Favors Human Papillary Thyroid Carcinoma Cell Apoptosis and Inhibits Epithelial Mesenchymal Transition via Wnt/ß-Catenin Pathway. Mol Cells 41:853-867 (2018). PubMed: 30165731
  • Agoston AT  et al. Columnar-Lined Esophagus Develops via Wound Repair in a Surgical Model of Reflux Esophagitis. Cell Mol Gastroenterol Hepatol 6:389-404 (2018). PubMed: 30186929
  • Chen Z  et al. Silencing the expression of copine-III enhances the sensitivity of hepatocellular carcinoma cells to the molecular targeted agent sorafenib. Cancer Manag Res 10:3057-3067 (2018). PubMed: 30214300
  • Dai J  et al. Down-regulation of long non-coding RNA ITGB2-AS1 inhibits osteosarcoma proliferation and metastasis by repressing Wnt/ß-catenin signalling and predicts favourable prognosis. Artif Cells Nanomed Biotechnol 46:S783-S790 (2018). PubMed: 30260245
  • Ma J  et al. EZH2-Mediated microRNA-139-5p Regulates Epithelial-Mesenchymal Transition and Lymph Node Metastasis of Pancreatic Cancer. Mol Cells 41:868-880 (2018). PubMed: 30304920
  • Liu Z  et al. CLCA4 inhibits cell proliferation and invasion of hepatocellular carcinoma by suppressing epithelial-mesenchymal transition via PI3K/AKT signaling. Aging (Albany NY) 10:2570-2584 (2018). PubMed: 30312171
  • Zheng X  et al. MicroRNA-221 promotes cell proliferation, migration, and differentiation by regulation of ZFPM2 in osteoblasts. Braz J Med Biol Res 51:e7574 (2018). PubMed: 30365725
  • Zhang B  et al. Metastasis-associated protein 2 promotes the metastasis of non-small cell lung carcinoma by regulating the ERK/AKT and VEGF signaling pathways. Mol Med Rep 17:4899-4908 (2018). PubMed: 29393472
  • Liu C  et al. MiR-144-3p promotes the tumor growth and metastasis of papillary thyroid carcinoma by targeting paired box gene 8. Cancer Cell Int 18:54 (2018). WB ; Human . PubMed: 29632436
  • Yang XH & Guo F miR-3147 serves as an oncomiR in vulvar squamous cell cancer via Smad4 suppression. Mol Med Rep 17:6397-6404 (2018). PubMed: 29512734
  • Yang Q  et al. Metformin Enhances the Effect of Regorafenib and Inhibits Recurrence and Metastasis of Hepatic Carcinoma After Liver Resection via Regulating Expression of Hypoxia Inducible Factors 2a (HIF-2a) and 30 kDa HIV Tat-Interacting Protein (TIP30). Med Sci Monit 24:2225-2234 (2018). PubMed: 29654226
  • Xu Y  et al. Dynamic Compression Promotes the Matrix Synthesis of Nucleus Pulposus Cells Through Up-Regulating N-CDH Expression in a Perfusion Bioreactor Culture. Cell Physiol Biochem 46:482-491 (2018). PubMed: 29614512
  • Chen Y  et al. Testicular orphan receptor 4 promotes tumor progression and implies poor survival through AKT3 regulation in seminoma. Cancer Sci 109:384-394 (2018). PubMed: 29197138
  • Zhou H  et al. Static compression down-regulates N-cadherin expression and facilitates loss of cell phenotype of nucleus pulposus cells in a disc perfusion culture. Biosci Rep 38:N/A (2018). PubMed: 29273678
  • Wang L  et al. Arrhythmogenic cardiomyopathy: Identification of desmosomal gene variations and desmosomal protein expression in variation carriers. Exp Ther Med 15:2255-2262 (2018). PubMed: 29456632
  • Zhu GJ  et al. Role of epithelial-mesenchymal transition markers E-cadherin, N-cadherin, ß-catenin and ZEB2 in laryngeal squamous cell carcinoma. Oncol Lett 15:3472-3481 (2018). PubMed: 29467869
  • Castosa R  et al. Hakai overexpression effectively induces tumour progression and metastasis in vivo. Sci Rep 8:3466 (2018). PubMed: 29472634
  • Vidovic D  et al. Transcriptional regulation of ependymal cell maturation within the postnatal brain. Neural Dev 13:2 (2018). PubMed: 29452604
  • Hu J  et al. TRPS1 Suppresses Breast Cancer Epithelial-mesenchymal Transition Program as a Negative Regulator of SUZ12. Transl Oncol 11:416-425 (2018). WB ; Human . PubMed: 29471243
  • Altshuler A  et al. RAS Regulates the Transition from Naive to Primed Pluripotent Stem Cells. Stem Cell Reports 10:1088-1101 (2018). WB ; Mouse . PubMed: 29456180
  • Li Y  et al. Long non-coding RNA NNT-AS1 affects progression of breast cancer through miR-142-3p/ZEB1 axis. Biomed Pharmacother 103:939-946 (2018). WB . PubMed: 29710510
  • Wu KH  et al. The apple polyphenol phloretin inhibits breast cancer cell migration and proliferation via inhibition of signals by type 2 glucose transporter. J Food Drug Anal 26:221-231 (2018). WB ; Human . PubMed: 29389559
  • Xu Q  et al. MicroRNA-876-5p inhibits epithelial-mesenchymal transition and metastasis of hepatocellular carcinoma by targeting BCL6 corepressor like 1. Biomed Pharmacother 103:645-652 (2018). WB ; Human . PubMed: 29679906
  • Saito K  et al. Loss of Stemness, EMT, and Supernumerary Tooth Formation in Cebpb-/-Runx2+/- Murine Incisors. Sci Rep 8:5169 (2018). IHC ; Mouse . PubMed: 29581460
  • Bechmann N  et al. Anti-Tumorigenic and Anti-Metastatic Activity of the Sponge-Derived Marine Drugs Aeroplysinin-1 and Isofistularin-3 against Pheochromocytoma In Vitro. Mar Drugs 16:N/A (2018). PubMed: 29783778
  • Yao Z  et al. Long non-coding RNA NRON is downregulated in HCC and suppresses tumour cell proliferation and metastasis. Biomed Pharmacother 104:102-109 (2018). WB ; Human . PubMed: 29772429
  • Liskova P  et al. Ectopic GRHL2 Expression Due to Non-coding Mutations Promotes Cell State Transition and Causes Posterior Polymorphous Corneal Dystrophy 4. Am J Hum Genet 102:447-459 (2018). IHC ; Human . PubMed: 29499165
  • Ma Y  et al. CD146 mediates an E-cadherin-to-N-cadherin switch during TGF-ß signaling-induced epithelial-mesenchymal transition. Cancer Lett 430:201-214 (2018). PubMed: 29777784
  • Chen W  et al. Downregulation of lncRNA OGFRP1 inhibits hepatocellular carcinoma progression by AKT/mTOR and Wnt/ß-catenin signaling pathways. Cancer Manag Res 10:1817-1826 (2018). PubMed: 29997441
  • Xu X  et al. PBX3/MEK/ERK1/2/LIN28/let-7b positive feedback loop enhances mesenchymal phenotype to promote glioblastoma migration and invasion. J Exp Clin Cancer Res 37:158 (2018). PubMed: 30016974
  • Jiang Z  et al. Aldolase A as a prognostic factor and mediator of progression via inducing epithelial-mesenchymal transition in gastric cancer. J Cell Mol Med 22:4377-4386 (2018). PubMed: 29992789
  • Zhao Y  et al. Prognostic value of association of OCT4 with LEF1 expression in esophageal squamous cell carcinoma and their impact on epithelial-mesenchymal transition, invasion, and migration. Cancer Med 7:3977-3987 (2018). PubMed: 29974668
  • Zhang Y  et al. TRIM27 functions as an oncogene by activating epithelial-mesenchymal transition and p-AKT in colorectal cancer. Int J Oncol 53:620-632 (2018). PubMed: 29767249
  • Chang L  et al. Melamine causes testicular toxicity by destroying blood-testis barrier in piglets. Toxicol Lett 296:114-124 (2018). PubMed: 30055240
  • Rogers CD  et al. A catenin-dependent balance between N-cadherin and E-cadherin controls neuroectodermal cell fate choices. Mech Dev 152:44-56 (2018). PubMed: 30009960
  • Zhang Y  et al. Apigenin suppresses mouse peritoneal fibrosis by down-regulating miR34a expression. Biomed Pharmacother 106:373-380 (2018). PubMed: 29966983
  • Li L  et al. MiR-98 modulates macrophage polarization and suppresses the effects of tumor-associated macrophages on promoting invasion and epithelial-mesenchymal transition of hepatocellular carcinoma. Cancer Cell Int 18:95 (2018). PubMed: 29989015
  • Zhang H  et al. Inhibition of the PI3K/Akt signaling pathway reverses sorafenib-derived chemo-resistance in hepatocellular carcinoma. Oncol Lett 15:9377-9384 (2018). PubMed: 29928334
  • Zeng K  et al. LACTB, a novel epigenetic silenced tumor suppressor, inhibits colorectal cancer progression by attenuating MDM2-mediated p53 ubiquitination and degradation. Oncogene N/A:N/A (2018). PubMed: 29899406
  • Han WQ  et al. Membrane rafts-redox signalling pathway contributes to renal fibrosis via modulation of the renal tubular epithelial-mesenchymal transition. J Physiol 596:3603-3616 (2018). PubMed: 29863758
  • Peng Y  et al. PDE4a predicts poor prognosis and promotes metastasis by inducing epithelial-mesenchymal transition in hepatocellular carcinoma. J Cancer 9:2389-2396 (2018). PubMed: 30026835
  • Su M  et al. miR-885-5p upregulation promotes colorectal cancer cell proliferation and migration by targeting suppressor of cytokine signaling. Oncol Lett 16:65-72 (2018). WB ; Human . PubMed: 29928388
  • Lv JW  et al. Inhibition of microRNA-214 promotes epithelial-mesenchymal transition process and induces interstitial cystitis in postmenopausal women by upregulating Mfn2. Exp Mol Med 49:e357 (2017). WB . PubMed: 28729638
  • Feliciano A  et al. miR-99a reveals two novel oncogenic proteins E2F2 and EMR2 and represses stemness in lung cancer. Cell Death Dis 8:e3141 (2017). WB ; Human . PubMed: 29072692
  • Kearns VR  et al. The formation of a functional retinal pigment epithelium occurs on porous polytetrafluoroethylene substrates independently of the surface chemistry. J Mater Sci Mater Med 28:124 (2017). PubMed: 28707136
  • Kim JE  et al. TRPC6-mediated ERK1/2 Activation Regulates Neuronal Excitability via Subcellular Kv4.3 Localization in the Rat Hippocampus. Front Cell Neurosci 11:413 (2017). PubMed: 29326557
  • Rodriguez AM & Downs KM Visceral endoderm and the primitive streak interact to build the fetal-placental interface of the mouse gastrula. Dev Biol N/A:N/A (2017). PubMed: 28882402
  • Sun L  et al. Decreased expression of acetyl-CoA synthase 2 promotes metastasis and predicts poor prognosis in hepatocellular carcinoma. Cancer Sci 108:1338-1346 (2017). WB . PubMed: 28387999
  • Bi Y  et al. MicroRNA-7 functions as a tumor-suppressor gene by regulating ILF2 in pancreatic carcinoma. Int J Mol Med 39:900-906 (2017). WB ; Human . PubMed: 28259961
  • Wang R  et al. Downregulation of FKBP14 by RNA interference inhibits the proliferation, adhesion and invasion of gastric cancer cells. Oncol Lett 13:2811-2816 (2017). WB ; Human . PubMed: 28454471
  • Wang A  et al. Tumor-associated macrophages promote Ezrin phosphorylation-mediated epithelial-mesenchymal transition in lung adenocarcinoma through FUT4/LeY up-regulation. Oncotarget 8:28247-28259 (2017). PubMed: 28423676
  • Zhang L  et al. Doxycycline inhibits the cancer stem cell phenotype and epithelial-to-mesenchymal transition in breast cancer. Cell Cycle 16:737-745 (2017). PubMed: 27753527
  • Tseng JH  et al. miR-200c-driven Mesenchymal-To-Epithelial Transition is a Therapeutic Target in Uterine Carcinosarcomas. Sci Rep 7:3614 (2017). PubMed: 28620240
  • Wang Z  et al. N-Cadherin Maintains the Healthy Biology of Nucleus Pulposus Cells under High-Magnitude Compression. Cell Physiol Biochem 43:2327-2337 (2017). PubMed: 29073605
  • Lindsay AJ & McCaffrey MW Rab coupling protein mediated endosomal recycling of N-cadherin influences cell motility. Oncotarget 8:104717-104732 (2017). PubMed: 29285208
  • Kim JE & Kang TC p47Phox/CDK5/DRP1-Mediated Mitochondrial Fission Evokes PV Cell Degeneration in the Rat Dentate Gyrus Following Status Epilepticus. Front Cell Neurosci 11:267 (2017). PubMed: 28919853
  • Bellissimo T  et al. Thymic Epithelial Tumors phenotype relies on miR-145-5p epigenetic regulation. Mol Cancer 16:88 (2017). WB, IHC ; Human . PubMed: 28486946
  • Dai X  et al. Coaxial 3D bioprinting of self-assembled multicellular heterogeneous tumor fibers. Sci Rep 7:1457 (2017). IHC-P ; Human . PubMed: 28469183
  • Qiu M  et al. MicroRNA-200c suppresses cell growth and metastasis by targeting Bmi-1 and E2F3 in renal cancer cells. Exp Ther Med 13:1329-1336 (2017). WB ; Human . PubMed: 28413473
  • Qiao B  et al. MicroRNA-27a-3p Modulates the Wnt/ß-Catenin Signaling Pathway to Promote Epithelial-Mesenchymal Transition in Oral Squamous Carcinoma Stem Cells by Targeting SFRP1. Sci Rep 7:44688 (2017). WB ; Human . PubMed: 28425477
  • Sun H  et al. Overexpression of N-cadherin and ß-catenin correlates with poor prognosis in patients with nasopharyngeal carcinoma. Oncol Lett 13:1725-1730 (2017). IHC-P ; Human . PubMed: 28454316
  • Burch A  et al. A novel synaptic junction preparation for the identification and characterization of cleft proteins. PLoS One 12:e0174895 (2017). PubMed: 28362857
  • Jin Y  et al. Upregulation of long non-coding RNA PlncRNA-1 promotes proliferation and induces epithelial-mesenchymal transition in prostate cancer. Oncotarget 8:26090-26099 (2017). PubMed: 28212533
  • Shin H  et al. Tropomyosin isoform Tpm2.1 regulates collective and amoeboid cell migration and cell aggregation in breast epithelial cells. Oncotarget 8:95192-95205 (2017). PubMed: 29221121
  • Ouyang J  et al. The role of aplysia ras homolog I in colon cancer cell invasion and adhesion. Exp Ther Med 14:5193-5199 (2017). PubMed: 29201236
  • Gao T  et al. LncRNA HSP90AA1-IT1 promotes gliomas by targeting miR-885-5p-CDK2 pathway. Oncotarget 8:75284-75297 (2017). PubMed: 29088865
  • Kim JS  et al. Silibinin attenuates radiation-induced intestinal fibrosis and reverses epithelial-to-mesenchymal transition. Oncotarget 8:69386-69397 (2017). PubMed: 29050211
  • Li X  et al. Role of blocking ADAM10 hydrolysis site on N-cadherin by single-chain antibody in ventricular remodeling. Exp Ther Med 14:4215-4223 (2017). PubMed: 29067106
  • Li P  et al. Long-term load duration induces N-cadherin down-regulation and loss of cell phenotype of nucleus pulposus cells in a disc bioreactor culture. Biosci Rep 37:N/A (2017). PubMed: 28351894
  • Zu C  et al. MiR-590-3p suppresses epithelial-mesenchymal transition in intrahepatic cholangiocarcinoma by inhibiting SIP1 expression. Oncotarget 8:34698-34708 (2017). PubMed: 28423728
  • Wang JJ  et al. Effects of microRNA-136 on melanoma cell proliferation, apoptosis, and epithelial-mesenchymal transition by targetting PMEL through the Wnt signaling pathway. Biosci Rep 37:N/A (2017). PubMed: 28724603
  • Liu W  et al. Overexpression of non-SMC condensin I complex subunit G serves as a promising prognostic marker and therapeutic target for hepatocellular carcinoma. Int J Mol Med 40:731-738 (2017). PubMed: 28737823
  • Wu H  et al. Abnormal expression of HAX-1 is associated with cellular proliferation and migration in human hypopharyngeal squamous cell carcinoma. Mol Med Rep 16:4664-4670 (2017). PubMed: 28791389
  • Yttersian Sletta K  et al. Oxygen-dependent regulation of tumor growth and metastasis in human breast cancer xenografts. PLoS One 12:e0183254 (2017). PubMed: 28832662
  • Jacobsen K  et al. Convergent Akt activation drives acquired EGFR inhibitor resistance in lung cancer. Nat Commun 8:410 (2017). PubMed: 28871105
  • Zhang M  et al. MiR-381 inhibits migration and invasion in human gastric carcinoma through downregulatedting SOX4. Oncol Lett 14:3760-3766 (2017). PubMed: 28927144
  • Kim YH  et al. Senescent tumor cells lead the collective invasion in thyroid cancer. Nat Commun 8:15208 (2017). IHC . PubMed: 28489070
  • An M  et al. Different macrophages equally induce EMT in endometria of adenomyosis and normal. Reproduction 154:79-92 (2017). PubMed: 28495851
  • Zhang L  et al. Inhibition of CCR7 promotes NF-?B-dependent apoptosis and suppresses epithelial-mesenchymal transition in non-small cell lung cancer. Oncol Rep 37:2913-2919 (2017). PubMed: 28339080
  • Xu Z  et al. LARP1 is regulated by the XIST/miR-374a axis and functions as an oncogene in non-small cell lung carcinoma. Oncol Rep 38:3659-3667 (2017). PubMed: 29039571
  • Tan H  et al. miR-382 inhibits migration and invasion by targeting ROR1 through regulating EMT in ovarian cancer. Int J Oncol 48:181-90 (2016). PubMed: 26575700
  • Tian Y  et al. Serum deprivation response inhibits breast cancer progression by blocking transforming growth factor-ß signaling. Cancer Sci 107:274-80 (2016). PubMed: 26749136
  • Hou H  et al. Long form collapsin response mediator protein-1 promotes the migration and invasion of osteosarcoma cells. Oncol Lett 12:23-28 (2016). WB ; Human . PubMed: 27347094
  • Sun SH  et al. SIX1 coordinates with TGFß signals to induce epithelial-mesenchymal transition in cervical cancer. Oncol Lett 12:1271-1278 (2016). WB ; Human . PubMed: 27446426
  • Cui Y  et al. Asparaginyl endopeptidase promotes the invasion and metastasis of gastric cancer through modulating epithelial-to-mesenchymal transition and analysis of their phosphorylation signaling pathways. Oncotarget 7:34356-70 (2016). Human . PubMed: 27102302
  • Zhou L  et al. Dermal fibroblasts induce cell cycle arrest and block epithelial-mesenchymal transition to inhibit the early stage melanoma development. Cancer Med 5:1566-79 (2016). PubMed: 27061029
  • Zhou W  et al. MicroRNA-98 acts as a tumor suppressor in hepatocellular carcinoma via targeting SALL4. Oncotarget 7:74059-74073 (2016). WB ; Human . PubMed: 27677076
  • Zheng X  et al. High expression of lncRNA PVT1 promotes invasion by inducing epithelial-to-mesenchymal transition in esophageal cancer. Oncol Lett 12:2357-2362 (2016). WB . PubMed: 27698800
  • Zhao Y  et al. 14-3-3?/TGFßR1 promotes tumor metastasis in lung squamous cell carcinoma. Oncotarget 7:82972-82984 (2016). WB ; Human . PubMed: 27764818
  • Lan T  et al. Downregulation of ZEB2-AS1 decreased tumor growth and metastasis in hepatocellular carcinoma. Mol Med Rep 14:4606-4612 (2016). WB ; Human . PubMed: 27748842
  • You A  et al. Metformin sensitizes sorafenib to inhibit postoperative recurrence and metastasis of hepatocellular carcinoma in orthotopic mouse models. J Hematol Oncol 9:20 (2016). WB ; Human . PubMed: 26957312
  • Fischer KD  et al. Vitamin D Supplementation Reduces Induction of Epithelial-Mesenchymal Transition in Allergen Sensitized and Challenged Mice. PLoS One 11:e0149180 (2016). IHC-P ; Mouse . PubMed: 26872336
  • Mehta A  et al. Intrinsic hepatocyte dedifferentiation is accompanied by upregulation of mesenchymal markers, protein sialylation and core alpha 1,6 linked fucosylation. Sci Rep 6:27965 (2016). WB ; Rat . PubMed: 27328854
  • Xu L  et al. WNT pathway inhibitor pyrvinium pamoate inhibits the self-renewal and metastasis of breast cancer stem cells. Int J Oncol 48:1175-86 (2016). PubMed: 26781188
  • Thakur AK  et al. TAp73 loss favors Smad-independent TGF-ß signaling that drives EMT in pancreatic ductal adenocarcinoma. Cell Death Differ 23:1358-70 (2016). PubMed: 26943320
  • Wang Z  et al. The Role of PIWIL4, an Argonaute Family Protein, in Breast Cancer. J Biol Chem 291:10646-58 (2016). PubMed: 26957540
  • Celá P  et al. BMP signaling regulates the fate of chondro-osteoprogenitor cells in facial mesenchyme in a stage-specific manner. Dev Dyn 245:947-62 (2016). PubMed: 27264541
  • Ling G  et al. Epithelial-mesenchymal transition regulated by p38/MAPK signaling pathways participates in vasculogenic mimicry formation in SHG44 cells transfected with TGF-ß cDNA loaded lentivirus in vitro and in vivo. Int J Oncol 49:2387-2398 (2016). PubMed: 27748800
  • Feng S  et al. Proton pump inhibitor pantoprazole inhibits the proliferation, self-renewal and chemoresistance of gastric cancer stem cells via the EMT/ß-catenin pathways. Oncol Rep 36:3207-3214 (2016). PubMed: 27748935
  • Wang YC  et al. miR-221 targets HMGA2 to inhibit bleomycin-induced pulmonary fibrosis by regulating TGF-ß1/Smad3-induced EMT. Int J Mol Med 38:1208-16 (2016). PubMed: 27513632
  • Zhang J  et al. Hsp60 exerts a tumor suppressor function by inducing cell differentiation and inhibiting invasion in hepatocellular carcinoma. Oncotarget 7:68976-68989 (2016). PubMed: 27677587
  • Ye T  et al. Isoorientin induces apoptosis, decreases invasiveness, and downregulates VEGF secretion by activating AMPK signaling in pancreatic cancer cells. Onco Targets Ther 9:7481-7492 (2016). WB ; Human . PubMed: 28003763
  • Rodriguez JA  et al. Diminished expression of CRHR2 in human colon cancer promotes tumor growth and EMT via persistent IL-6/Stat3 signaling. Cell Mol Gastroenterol Hepatol 1:610-630 (2015). PubMed: 26495412
  • Fu XT  et al. Macrophage-secreted IL-8 induces epithelial-mesenchymal transition in hepatocellular carcinoma cells by activating the JAK2/STAT3/Snail pathway. Int J Oncol 46:587-96 (2015). PubMed: 25405790
  • Secq V  et al. Stromal SLIT2 impacts on pancreatic cancer-associated neural remodeling. Cell Death Dis 6:e1592 (2015). WB, IP . PubMed: 25590802
  • Nishioka M  et al. Fibroblast-epithelial cell interactions drive epithelial-mesenchymal transition differently in cells from normal and COPD patients. Respir Res 16:72 (2015). IHC-P ; Human . PubMed: 26081431
  • Liu L  et al. SALL4 as an Epithelial-Mesenchymal Transition and Drug Resistance Inducer through the Regulation of c-Myc in Endometrial Cancer. PLoS One 10:e0138515 (2015). WB ; Human . PubMed: 26407074
  • Rollo BN  et al. Why are enteric ganglia so small? Role of differential adhesion of enteric neurons and enteric neural crest cells. F1000Res 4:113 (2015). PubMed: 26064478
  • Yotsumoto F  et al. NG2 proteoglycan-dependent recruitment of tumor macrophages promotes pericyte-endothelial cell interactions required for brain tumor vascularization. Oncoimmunology 4:e1001204 (2015). PubMed: 26137396
  • Xu S  et al. Downregulation of long noncoding RNA MALAT1 induces epithelial-to-mesenchymal transition via the PI3K-AKT pathway in breast cancer. Int J Clin Exp Pathol 8:4881-91 (2015). WB ; Human . PubMed: 26191181
  • Brusgard JL  et al. RUNX2 and TAZ-dependent signaling pathways regulate soluble E-Cadherin levels and tumorsphere formation in breast cancer cells. Oncotarget 6:28132-50 (2015). WB ; Human . PubMed: 26320173
  • Sharma P  et al. Evolutionarily conserved intercalated disc protein Tmem65 regulates cardiac conduction and connexin 43 function. Nat Commun 6:8391 (2015). WB, ICC/IF . PubMed: 26403541
  • Ma W  et al. Overexpression of N-myc downstream-regulated gene 1 inhibits human glioma proliferation and invasion via phosphoinositide 3-kinase/AKT pathways. Mol Med Rep 12:1050-8 (2015). IF ; Human . PubMed: 25777142
  • Tanaka T  et al. CD24 expression as a marker for predicting clinical outcome and invasive activity in uterine cervical cancer. Oncol Rep 34:2282-8 (2015). WB ; Human . PubMed: 26351781
  • Guckenberger DJ  et al. High-density self-contained microfluidic KOALA kits for use by everyone. J Lab Autom 20:146-53 (2015). ICC/IF . PubMed: 25424385
  • El-Hayek S & Clarke HJ Follicle-Stimulating Hormone Increases Gap Junctional Communication Between Somatic and Germ-Line Follicular Compartments During Murine Oogenesis. Biol Reprod 93:47 (2015). WB, IHC-P ; Mouse . PubMed: 26063870
  • Carthy JM  et al. Versican V1 Overexpression Induces a Myofibroblast-Like Phenotype in Cultured Fibroblasts. PLoS One 10:e0133056 (2015). WB ; Mouse . PubMed: 26176948
  • Pieroh P  et al. Temporal dynamics of glyoxalase 1 in secondary neuronal injury. PLoS One 9:e87364 (2014). ICC/IF ; Rat . PubMed: 24498315
  • Yoshida T  et al. Eribulin mesilate suppresses experimental metastasis of breast cancer cells by reversing phenotype from epithelial-mesenchymal transition (EMT) to mesenchymal-epithelial transition (MET) states. Br J Cancer 110:1497-505 (2014). IHC-P ; Mouse . PubMed: 24569463
  • Shamir ER  et al. Twist1-induced dissemination preserves epithelial identity and requires E-cadherin. J Cell Biol 204:839-56 (2014). Mouse . PubMed: 24590176
  • Tucci V  et al. Dominant ß-catenin mutations cause intellectual disability with recognizable syndromic features. J Clin Invest 124:1468-82 (2014). IP . PubMed: 24614104
  • Chao CH  et al. MicroRNA-205 signaling regulates mammary stem cell fate and tumorigenesis. J Clin Invest 124:3093-106 (2014). WB . PubMed: 24911147
  • Garcin PO & Panté N Cell migration is another player of the minute virus of mice infection. Virology 468-470C:150-159 (2014). Mouse . PubMed: 25173091
  • Herr KJ  et al. Loss of a-catenin elicits a cholestatic response and impairs liver regeneration. Sci Rep 4:6835 (2014). PubMed: 25355493
  • Woods K  et al. Effects of epithelial to mesenchymal transition on T cell targeting of melanoma cells. Front Oncol 4:367 (2014). ICC/IF ; Human . PubMed: 25566505
  • Xiao Q  et al. Matrix metalloproteinase-8 promotes vascular smooth muscle cell proliferation and neointima formation. Arterioscler Thromb Vasc Biol 34:90-8 (2014). PubMed: 24158518
  • Forteza R  et al. Par-complex aPKC and Par3 cross-talk with innate immunity NF-?B pathway in epithelial cells. Biol Open 2:1264-9 (2013). PubMed: 24244864
  • Paul C & Robaire B Impaired function of the blood-testis barrier during aging is preceded by a decline in cell adhesion proteins and GTPases. PLoS One 8:e84354 (2013). WB ; Rat . PubMed: 24391944
  • Guillaumond F  et al. Strengthened glycolysis under hypoxia supports tumor symbiosis and hexosamine biosynthesis in pancreatic adenocarcinoma. Proc Natl Acad Sci U S A 110:3919-24 (2013). Mouse . PubMed: 23407165
  • Berghoff AS  et al. Invasion patterns in brain metastases of solid cancers. Neuro Oncol N/A:N/A (2013). PubMed: 24084410
  • Mendoza-Naranjo A  et al. Targeting Cx43 and N-cadherin, which are abnormally upregulated in venous leg ulcers, influences migration, adhesion and activation of Rho GTPases. PLoS One 7:e37374 (2012). WB, IHC-Fr ; Human, Mouse, Rat . PubMed: 22615994
  • Gaertner A  et al. In vitro functional analyses of arrhythmogenic right ventricular cardiomyopathy-associated desmoglein-2-missense variations. PLoS One 7:e47097 (2012). IF ; Human . PubMed: 23071725
  • Shi Y  et al. Human cerebral cortex development from pluripotent stem cells to functional excitatory synapses. Nat Neurosci 15:477-86, S1 (2012). ICC/IF ; Human . PubMed: 22306606
  • Greenbaum AM  et al. N-cadherin in osteolineage cells is not required for maintenance of hematopoietic stem cells. Blood 120:295-302 (2012). IHC-P ; Mouse . PubMed: 22323481
  • Plageman TF  et al. Shroom3 and a Pitx2-N-cadherin pathway function cooperatively to generate asymmetric cell shape changes during gut morphogenesis. Dev Biol 357:227-34 (2011). IHC-Fr ; Mouse . PubMed: 21726547
  • Vuoriluoto K  et al. Vimentin regulates EMT induction by Slug and oncogenic H-Ras and migration by governing Axl expression in breast cancer. Oncogene 30:1436-48 (2011). PubMed: 21057535
  • Shima N  et al. Increased Proliferation and Replicative Lifespan of Isolated Human Corneal Endothelial Cells with L-Ascorbic acid 2-phosphate. Invest Ophthalmol Vis Sci 52:8711-7 (2011). PubMed: 21980003
  • Maïga O  et al. Identification of mitogen-activated protein/extracellular signal-responsive kinase kinase 2 as a novel partner of the scaffolding protein human homolog of disc-large. FEBS J 278:2655-65 (2011). PubMed: 21615688
  • Stan A  et al. Essential cooperation of N-cadherin and neuroligin-1 in the transsynaptic control of vesicle accumulation. Proc Natl Acad Sci U S A 107:11116-21 (2010). ICC/IF ; Rat . PubMed: 20534458
  • Takayama Y & Mizumachi K Inhibitory effect of lactoferrin on hypertrophic differentiation of ATDC5 mouse chondroprogenitor cells. Biometals 23:477-84 (2010). WB ; Mouse . PubMed: 20094900
  • Poore CP  et al. Cdk5-mediated phosphorylation of delta-catenin regulates its localization and GluR2-mediated synaptic activity. J Neurosci 30:8457-67 (2010). WB ; Mouse . PubMed: 20573893
  • Gjerdrum C  et al. Axl is an essential epithelial-to-mesenchymal transition-induced regulator of breast cancer metastasis and patient survival. Proc Natl Acad Sci U S A 107:1124-9 (2010). WB ; Human . PubMed: 20080645
  • Smyth JW  et al. Limited forward trafficking of connexin 43 reduces cell-cell coupling in stressed human and mouse myocardium. J Clin Invest 120:266-79 (2010). WB . PubMed: 20038810
  • Vallier L  et al. Signaling pathways controlling pluripotency and early cell fate decisions of human induced pluripotent stem cells. Stem Cells 27:2655-66 (2009). ICC/IF ; Human . PubMed: 19688839
  • Smith AN  et al. Stage-dependent modes of Pax6-Sox2 epistasis regulate lens development and eye morphogenesis. Development 136:2977-85 (2009). IHC ; Mouse . PubMed: 19666824
  • Vallier L  et al. Early cell fate decisions of human embryonic stem cells and mouse epiblast stem cells are controlled by the same signalling pathways. PLoS One 4:e6082 (2009). ICC/IF ; Human . PubMed: 19564924
  • Zhang SW  et al. Aconitine alters connexin43 phosphorylation status and [Ca2+] oscillation patterns in cultured ventricular myocytes of neonatal rats. Toxicol In Vitro 21:1476-85 (2007). PubMed: 17728094

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

Sign up