N-Octadecanoylphytosphingosine (Ceramide III), sphingolipid ceramide analog (ab144149)

Overview

  • Product name

    N-Octadecanoylphytosphingosine (Ceramide III), sphingolipid ceramide analog
  • Description

    Analog of sphingolipid ceramide
  • Alternative names

    • Ceramide III
  • Biological description

    Analog of sphingolipid ceramide. Component of stratum corneum. Anti-inflammatory potential. Use in sphingolipid ceramide studies and as internal standard.
  • Purity

    > 98%
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    N-[(2S,3S,4R)-1,3,4-Trihydroxyoctadecan-2-yl]octadecanamide
  • Molecular weight

    583.98
  • Molecular formula

    C36H73NO4
  • PubChem identifier

    9898642
  • Storage instructions

    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CCCCCCCCCCCCCCCCCC(=O)N[C@@H](CO)[C@@H]([C@@H](CCCCCCCCCCCCCC)O)O
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:

  • Kim BH  et al. Phytosphingosine derivatives ameliorate skin inflammation by inhibiting NF-?B and JAK/STAT signaling in keratinocytes and mice. J Invest Dermatol 134:1023-32 (2014). Read more (PubMed: 24177187) »
  • Raudenkolb S  et al. Polymorphism of ceramide 3. Part 1: an investigation focused on the head group of N-octadecanoylphytosphingosine. Chem Phys Lipids 123:9-17 (2003). Read more (PubMed: 12637161) »
  • Ohta N & Hatta I Interaction among molecules in mixtures of ceramide/stearic acid, ceramide/cholesterol and ceramide/stearic acid/cholesterol. Chem Phys Lipids 115:93-105 (2002). Read more (PubMed: 12047901) »

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES, NOT FOR USE IN HUMANS"
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