N-Octanoylphytosphingosine, sphingolipid ceramide analog (ab144123)

Overview

  • Product name

    N-Octanoylphytosphingosine, sphingolipid ceramide analog
  • Description

    Analog of sphingolipid ceramide
  • Alternative names

    • N-octanoyl 4-hydroxysphinganine
  • Biological description

    Analog of sphingolipid ceramide. Possible role in ceramide biosynthesis, apoptosis and anticancer potential. Use in sphingolipid ceramide studies and as internal standard.

    See similar compounds
  • Purity

    > 98%
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    N-[(2S,3S,4R)-1,3,4-Trihydroxyoctadecan-2-yl]octanamide
  • Molecular weight

    443.70
  • Molecular formula

    C26H53NO4
  • PubChem identifier

    11517895
  • Storage instructions

    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in ethanol
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CCCCCCCCCCCCCC[C@H]([C@H]([C@H](CO)NC(=O)CCCCCCC)O)O
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:

  • Rives A  et al. Asymmetric synthesis and cytotoxic activity of isomeric phytosphingosine derivatives. Org Biomol Chem 9:8163-70 (2011). Read more (PubMed: 21986639) »
  • Omae F  et al. DES2 protein is responsible for phytoceramide biosynthesis in the mouse small intestine. Biochem J 379:687-95 (2004). Read more (PubMed: 14731113) »
  • Hwang O  et al. Synthetic phytoceramides induce apoptosis with higher potency than ceramides. Mol Pharmacol 59:1249-55 (2001). Read more (PubMed: 11306710) »

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