Overview

  • Product name

    N-Oleoylethanolamine, PPAR-alpha agonist
  • Description

    Potent PPAR-α agonist
  • Biological description

    Potent PPAR-α agonist (EC50 = 120 nM). Anandamide (ab120087, ab120429) analog. Binds to cannabinoid receptor GPR119. Shows anti-ischemic and neuroprotective effects in vivo. Orally active.
  • Purity

    > 98%
  • CAS Number

    111-58-0
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Li W  et al. Endogenous ceramide contributes to the transcytosis of oxLDL across endothelial cells and promotes its subendothelial retention in vascular wall. Oxid Med Cell Longev 2014:823071 (2014). Read more (PubMed: 24817993) »
  • Zhou Y  et al. Orally administered oleoylethanolamide protects mice from focal cerebral ischemic injury by activating peroxisome proliferator-activated receptor a. Neuropharmacology 63:242-9 (2012). Read more (PubMed: 22480617) »
  • Sun Y  et al. Cannabinoid activation of PPAR alpha; a novel neuroprotective mechanism. Br J Pharmacol 152:734-43 (2007). Read more (PubMed: 17906680) »

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