Key features and details
- Endogenous lipid anorectic hormone which significantly reduced food intake in a dose-dependent fashion
- CAS Number: 108321-22-8
- Purity: > 98%
- Form / State: Solid
- Source: Synthetic
Product nameN-Palmitoyl phosphatidylethanolamine, Endogenous lipid anorectic hormone
DescriptionEndogenous lipid anorectic hormone which significantly reduced food intake in a dose-dependent fashion
- C16:0 NAPE
Endogenous lipid which significantly reduced food intake in a dose-dependent fashion when administered to rats and mice without causing taste aversion. Found to enter the brain (concentrating in the hypothalamus) when administered systemically and also reduced food intake when infused intracerebroventricularly (nanomolar concentrations), suggesting that mediation of effects is via the CNS. Chronic infusion resulted in a reduction of both food intake and body weight, suggesting that NAPE and long-acting NAPE analogs may be novel therapeutic targets for the treatment of obesity.
Storage instructionsStore at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
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To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab145219 has not yet been referenced specifically in any publications.