Overview

  • Product name

    N6-Cyclopentyladenosine (CPA), A1 agonist
  • Description

    Potent, selective A1 agonist
  • Alternative names

    • CPA
  • Biological description

    Potent and selective adenosine A1 receptor agonist (Ki values are 2.3, 790 and 43 nM for human A1, A2A and A3 receptors, respectively). Centrally active following systemic administration in vivo. Anticonvulsant, with cardiovacular actions, and effects on sleep regulation.
  • Purity

    > 99%
  • CAS Number

    41552-82-3
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Klotz KN Adenosine receptors and their ligands. Naunyn Schmiedebergs Arch Pharmacol 362:382-91 (2000). Read more (PubMed: 11111832) »
  • Schwierin B  et al. Effects of N6-cyclopentyladenosine and caffeine on sleep regulation in the rat. Eur J Pharmacol 300:163-71 (1996). Read more (PubMed: 8739204) »
  • Williams M  et al. Evaluation of the binding of the A-1 selective adenosine radioligand, cyclopentyladenosine (CPA), to rat brain tissue. Naunyn Schmiedebergs Arch Pharmacol 332:179-83 (1986). Read more (PubMed: 3703020) »
See all 3 Publications for this product

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