Anti-NAF1 antibody (ab122323)
Key features and details
- Rabbit polyclonal to NAF1
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-NAF1 antibody
See all NAF1 primary antibodies -
Description
Rabbit polyclonal to NAF1 -
Host species
Rabbit -
Tested applications
Suitable for: IHC-Pmore details -
Species reactivity
Reacts with: Human -
Immunogen
antigen: EIFGPVAHPF YVLRFNSSDH IESKGIKIKE TMYFAPSMKD FTQYIFTEKL KQDKGSDASW KNDQEPPPEA LDFSDDEKEK EAKQRKKSQI QGRK, corresponding to amino acids 242-335 of Human NAF1 (Q96HR8).
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Positive control
- IHC: Human esophagus tissue
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. -
Storage buffer
pH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 59% PBS, 40% Glycerol (glycerin, glycerine) -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab122323 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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IHC-P |
1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
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Notes |
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IHC-P
1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
Target
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Function
RNA-binding protein required for the maturation of box H/ACA snoRNPs complex and ribosome biogenesis. During assembly of the H/ACA snoRNPs complex, it associates with the complex and disapears during maturation of the complex and is replaced by NOLA1/GAR1 to yield mature H/ACA snoRNPs complex. Probably competes with NOLA1/GAR1 for binding with DKC1/NOLA4. -
Sequence similarities
Belongs to the NAF1 family. -
Cellular localization
Cytoplasm. Nucleus. Shuttles between the cytoplasm and the nucleus. Absent from the nucleolus. - Information by UniProt
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Database links
- Entrez Gene: 92345 Human
- SwissProt: Q96HR8 Human
- Unigene: 129095 Human
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Alternative names
- H/ACA ribonucleoprotein complex non-core subunit NAF1 antibody
- hNAF1 antibody
- Naf1 antibody
see all
Images
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab122323 has not yet been referenced specifically in any publications.