Overview

  • Product name

    Anti-NAIP antibody [EPR6169]
    See all NAIP primary antibodies
  • Description

    Rabbit monoclonal [EPR6169] to NAIP
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
    Unsuitable for: IHC-P or IP
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to residues in Human NAIP. (Uniprot: Q13075)

  • Positive control

    • Human tonsil, Human placenta and fetal kidney cell lysates.
  • General notes

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

     

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.

    This product is a recombinant rabbit monoclonal antibody.

Properties

Applications

Our Abpromise guarantee covers the use of ab129079 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Detects a band of approximately 160 kDa.
  • Application notes
    Is unsuitable for IHC-P or IP.
  • Target

    • Function

      Prevents motor-neuron apoptosis induced by a variety of signals. Possible role in the prevention of spinal muscular atrophy that seems to be caused by inappropriate persistence of motor-neuron apoptosis: mutated or deleted forms of NAIP have been found in individuals with severe spinal muscular atrophy.
    • Tissue specificity

      Expressed in motor neurons, but not in sensory neurons. Found in liver and placenta, and to a lesser extent in spinal cord.
    • Sequence similarities

      Contains 3 BIR repeats.
      Contains 1 NACHT domain.
    • Information by UniProt
    • Database links

    • Alternative names

      • Baculoviral IAP repeat containing 1 antibody
      • Baculoviral IAP repeat-containing protein 1 antibody
      • BIRC 1 antibody
      • BIRC1 antibody
      • BIRC1_HUMAN antibody
      • Birc1a antibody
      • FLJ42520 antibody
      • NAIP antibody
      • Naip1 antibody
      • Neuronal apoptosis inhibitory protein antibody
      • NLR family apoptosis inhibitory protein antibody
      • NLR family BIR domain containing 1 antibody
      • NLRB 1 antibody
      • NLRB1 antibody
      • Nucleotide binding oligomerization domain leucine rich repeat and BIR domain containing 1 antibody
      • Psi neuronal apoptosis inhibitory protein antibody
      • psiNAIP antibody
      • Similar to occludin antibody
      see all

    Images

    • All lanes : Anti-NAIP antibody [EPR6169] (ab129079) at 1/1000 dilution

      Lane 1 : Human tonsil cell lysate
      Lane 2 : Human placenta cell lysate
      Lane 3 : Human fetal kidney cell lysate

      Lysates/proteins at 10 µg per lane.

      Secondary
      All lanes : Goat Anti-rabbit HRP
    • Equilibrium disassociation constant (KD)
      Learn more about KD

      Click here to learn more about KD

    References

    This product has been referenced in:

    • Wu MS  et al. Smac mimetics in combination with TRAIL selectively target cancer stem cells in nasopharyngeal carcinoma. Mol Cancer Ther 12:1728-37 (2013). WB . Read more (PubMed: 23699656) »
    See 1 Publication for this product

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab129079.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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