Overview

  • Product name

    Naringin, flavanone glycoside
  • Description

    A flavanone glycoside
  • Biological description

    A flavanone glycoside. Neuroprotective. Activates Nrf2. Inhibits expression of pro-inflammatory mediators.
  • Purity

    > 97%
  • CAS Number

    10236-47-2
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    7-[(2R,3S,4R,5R,6S)-4,5-Dihydroxy-6-(hydroxymethyl)-3-[(2S,3R,4R,5R,6S)-3,4,
    5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-5-hydroxy-2-(4-hydroxyphenyl)-2,3-dihydrochromen-4-one
  • Molecular weight

    580.53
  • Molecular formula

    C27H32O14
  • PubChem identifier

    45358136
  • Storage instructions

    Store at Room Temperature. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in DMSO to 100 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CC1C(C(C(C(O1)OC2C(C(C(OC2OC3=CC(=C4C(=O)CC(OC4=C3)C5=CC=C(C=C5)O)O)CO)O)O)O)O)O
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:

  • Zhai YK  et al. [Effects of naringin on proliferation, differentiation and maturation of rat calvarial osteoblasts in vitro]. Zhongguo Zhong Yao Za Zhi 38:105-11 (2013). Read more (PubMed: 23596885) »
  • Gopinath K & Sudhandiran G Naringin modulates oxidative stress and inflammation in 3-nitropropionic acid-induced neurodegeneration through the activation of nuclear factor-erythroid 2-related factor-2 signalling pathway. Neuroscience 227:134-43 (2012). Read more (PubMed: 22871521) »
  • Tsai YJ & Tsai TH Mesenteric lymphatic absorption and the pharmacokinetics of naringin and naringenin in the rat. J Agric Food Chem 60:12435-42 (2012). Read more (PubMed: 23210543) »

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES, NOT FOR USE IN HUMANS"
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