Key features and details
- Rabbit polyclonal to NAS6
- Suitable for: WB, IP
- Reacts with: Saccharomyces cerevisiae
- Isotype: IgG
Product nameAnti-NAS6 antibody
DescriptionRabbit polyclonal to NAS6
Tested applicationsSuitable for: WB, IPmore details
Species reactivityReacts with: Saccharomyces cerevisiae
Recombinant full length Saccharomyces cerevisiae NAS6 protein, expressed in E. coli.
- Crude extract of S. cerevisiae
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Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
Storage bufferpH: 6
Preservative: 0.09% Sodium azide
Constituents: PBS, 0.1% BSA, 50% Glycerol (glycerin, glycerine)
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab91447 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB: 1/5000. Predicted molecular weight: 26 kDa.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
RelevanceNAS6 (p28) is a proteasome-interacting protein which acts as a chaperone to assemble the base sub-complex of the 19S RP which is involved in the ATP-dependent degradation of ubiquitinated proteins. NAS6 is composed of 226 amino acid residues with calculated molecular masses of 24.4kD.
Cellular localizationCytosol; Nucleus; Proteasome complex
- Nas6p antibody
- ortholog of human oncoprotein gankyrin, which interacts with the Rb tumor suppressor and CDK4/6 antibody
- Probable 26S proteasome regulatory subunit p28 antibody
ab91447 has been referenced in 2 publications.
- Greene ER et al. Specific lid-base contacts in the 26s proteasome control the conformational switching required for substrate degradation. Elife 8:N/A (2019). PubMed: 31778111
- Rousseau A & Bertolotti A An evolutionarily conserved pathway controls proteasome homeostasis. Nature 536:184-9 (2016). WB . PubMed: 27462806