Native Collagen V protein (ab7530)
Key features and details
- Expression system: Native
- Suitable for: WB, IP, ELISA
Description
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Product name
Native Collagen V protein
See all Collagen V proteins and peptides -
Biological activity
Collagen taken from bovine species. -
Expression system
Native -
Protein length
Full length protein -
Animal free
No -
Nature
Native
Associated products
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Related Products
Specifications
Our Abpromise guarantee covers the use of ab7530 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
Western blot
Immunoprecipitation
ELISA
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Form
Liquid -
Additional notes
This product reacts with anti-Collagen Type V. Reaction with anti-Collagen I, II, III, IV or VI is negligible (typically less than 1% cross reactivity was detected by ELISA).
Collagen taken from bovine species.
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Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Constituent: 0.82% Sodium acetate
General Info
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Alternative names
- AB collagen
- Alpha 1 type V collagen
- Alpha 2 type V collagen
see all -
Function
Type V collagen is a member of group I collagen (fibrillar forming collagen). It is a minor connective tissue component of nearly ubiquitous distribution. Type V collagen binds to DNA, heparan sulfate, thrombospondin, heparin, and insulin. -
Involvement in disease
Ehlers-Danlos syndrome 1
Ehlers-Danlos syndrome 2 -
Sequence similarities
Belongs to the fibrillar collagen family.
Contains 1 fibrillar collagen NC1 domain.
Contains 1 laminin G-like domain. -
Domain
The C-terminal propeptide, also known as COLFI domain, have crucial roles in tissue growth and repair by controlling both the intracellular assembly of procollagen molecules and the extracellular assembly of collagen fibrils. It binds a calcium ion which is essential for its function. -
Post-translational
modificationsProlines at the third position of the tripeptide repeating unit (G-X-Y) are hydroxylated in some or all of the chains.
Sulfated on 40% of tyrosines. -
Cellular localization
Secreted > extracellular space > extracellular matrix. - Information by UniProt
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab7530 has not yet been referenced specifically in any publications.