Description

  • Product name

    Native Cow 160 kD Neurofilament Medium protein
  • Purity

    > 95 % SDS-PAGE.
    Purity is greater than 98.0% as determined by RP-HPLC and SDS-PAGE.
  • Expression system

    Native
  • Protein length

    Full length protein
  • Animal free

    No
  • Nature

    Native
    • Species

      Cow
    • Predicted molecular weight

      160 kDa
    • Additional sequence information

      Source = bovine spinal cord

Specifications

Our Abpromise guarantee covers the use of ab73759 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    ELISA

    Western blot

  • Form

    Lyophilised
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 7.50
    Constituents: 36% Urea, 0.164% Sodium phosphate, 0.0308% DTT, 0.0292% EDTA

  • Reconstitution
    Reconstitute in sterile 18MO-cm H2O. Upon reconstitution NRFab73759 should be stored at 4°C between 2-7 days and for future use below -18°C. Please prevent freeze-thaw cycles.

General Info

  • Alternative names

    • 150kDa medium
    • NEF3
    • NEFM
    • Neurofilament 3
    • NF160
    • NFM
    see all
  • Relevance

    Neurofilaments are the 10nm or intermediate filament proteins found specifically in neurons, and are composed predominantly of three major proteins called neurofilament light (NF-L), neurofilament medium (NF-M) and neurofilament heavy (NF-H). Neurofilament medium runs on SDS-PAGE gels in the range 145-170 kDa, with some variation in different species. Antibodies to this protein are useful to identify neurons and their processes in tissue sections and in tissue culture. Neurofilament medium can also be useful in studies of neurofilament accumulations seen in many neurological diseases, such as Lou Gehrig's disease or Alzheimer's disease.
  • Cellular localization

    Cytoplasm

Images

References

ab73759 has not yet been referenced specifically in any publications.

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