Overview

Description

  • Nature

    Native
  • Source

    Native
  • Amino Acid Sequence
    • Accession
    • Species

      Cow
    • Molecular weight

      25 kDa
    • Amino acids

      1 to 221
    • Additional sequence information

      Purified from bovine red blood cells.

Specifications

Our Abpromise guarantee covers the use of ab218002 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Purity

    > 90 % SDS-PAGE.

  • Form

    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on Dry Ice. Upon delivery aliquot. Store at -80°C. Avoid freeze / thaw cycle.

    pH: 7.6
    Constituents: 0.24% Tris, 0.02% Beta mercaptoethanol, 0.11% ATP, 0.05% Magnesium chloride, 10% Glycerol, 0.23% Sodium chloride

General Info

  • Alternative names

    • 26S proteasome non-ATPase regulatory subunit 9
    • 26S proteasome regulatory subunit p27
    • Homolog of rat Bridge 1
    • p27
    • Proteasome (prosome macropain) 26S subunit non ATPase 9
    • Proteasome 26S non ATPase regulatory subunit 9
    • Proteasome 26S subunit non ATPase 9
    • Psmd9
    • PSMD9_HUMAN
    • Rpn4
    see all
  • Function

    Acts as a chaperone during the assembly of the 26S proteasome, specifically of the base subcomplex of the PA700/19S regulatory complex (RC). During the base subcomplex assembly is part of an intermediate PSMD9:PSMC6:PSMC3 module, also known as modulator trimer complex; PSMD9 is released during the further base assembly process.
  • Tissue specificity

    Expressed in all tissues tested, highly expressed in liver and kidney.
  • Sequence similarities

    Belongs to the proteasome subunit p27 family.
    Contains 1 PDZ (DHR) domain.
  • Information by UniProt

Images

  • 4% native-PAGE analysis of ab218002 (3 μg):

    Lane 1: Coomassie-staining

    Lane 2: the proteasome activity was determined by an overlay assay using Suc-LLVY-AMC as the substrate 

  • SDS-PAGE analysis of ab218002 (5 μg).

References

ab218002 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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