Description

  • Product name

    Native Cynomolgus monkey Transferrin protein
    See all Transferrin proteins and peptides
  • Purity

    > 95 % SDS-PAGE.

  • Expression system

    Native
  • Protein length

    Full length protein
  • Animal free

    No
  • Nature

    Native
    • Species

      Cynomolgus monkey
    • Predicted molecular weight

      80 kDa
    • Additional sequence information

      Prepared from plasma of donor monkeys that have been individually tested for B-Virus (Herpes Virus Simiae) and found to be negative.

Specifications

Our Abpromise guarantee covers the use of ab198644 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Form

    Lyophilised
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at -80°C. Avoid freeze / thaw cycle.

    pH: 7.40
    Constituents: 0.87% Sodium chloride, 99% Phosphate Buffer

  • Reconstitution
    We suggest the addition of de-ionized H2O to the original volume, followed by gentle swirling and/or vortexing to ensure adequate homogenization. If further dilution is required, we suggest using the lyophilization buffer.

General Info

  • Alternative names

    • Apotransferrin
    • Beta 1 metal binding globulin
    • Beta-1 metal-binding globulin
    • DKFZp781D0156
    • PRO1400
    • PRO1557
    • PRO2086
    • Serotransferrin
    • Serotransferrin precursor
    • Siderophilin
    • TF
    • TFQTL1
    • Transferin
    • Transferrin
    • TRFE_HUMAN
    see all
  • Function

    Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation.
  • Tissue specificity

    Expressed by the liver and secreted in plasma.
  • Involvement in disease

    Defects in TF are the cause of atransferrinemia (ATRAF) [MIM:209300]. Atransferrinemia is rare autosomal recessive disorder characterized by iron overload and hypochromic anemia.
  • Sequence similarities

    Belongs to the transferrin family.
    Contains 2 transferrin-like domains.
  • Cellular localization

    Secreted.
  • Information by UniProt

Images

  • SDS PAGE analysis of ab198644:
    Lane 1: 5 μg, under reduced and heated conditions;
    Lane 2: 10 μg, under reduced and heated conditions;
    Lane 3: 20 μg, under reduced and heated conditions.
    Lane 4: 5 μg, under non reduced and not heated conditions;
    Lane 5: 10 μg, under non reduced and not heated conditions;
    Lane 6: 20 μg, under non reduced and not heated conditions.

References

ab198644 has not yet been referenced specifically in any publications.

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