Native Human AHSG protein (ab93727)

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Key features and details

  • Expression system: Native
  • Purity: > 95% SDS-PAGE
  • Suitable for: SDS-PAGE

Description

  • Product name

    Native Human AHSG protein
    See all AHSG proteins and peptides

  • Purity

    > 95 % SDS-PAGE.

  • Expression system

    Native

  • Protein length

    Full length protein

  • Animal free

    No

  • Nature

    Native

    • Species

      Human

Associated products

Specifications

Our Abpromise guarantee covers the use of ab93727 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Form

    Lyophilized

  • Additional notes

    Prepared from plasma shown to be non reactive for HbsAG, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.316% Tris HCl, 1.16% Sodium chloride

  • Reconstitution
    Reconstitute in deionized water.

General Info

  • Alternative names

    • 59 kDa bone sialic acid-containing protein
    • A2HS
    • Aa2-066
    • AHS
    • Ahsg
    • Ahsg alpha-2-HS-glycoprotein
    • Alpha 2 HS Glycoprotein
    • Alpha 2 Z globulin
    • Alpha-2-HS-glycoprotein
    • Alpha-2-HS-glycoprotein chain B
    • Alpha-2-Z-globulin
    • Asialofetuin
    • Ba alpha 2 glycoprotein
    • Ba-alpha-2-glycoprotein
    • BSP
    • Countertrypin
    • Fetua
    • FETUA_HUMAN
    • Fetuin , mouse, homolog of
    • Fetuin A
    • Fetuin-A
    • Glycoprotein PP63
    • HSGA
    • pp63
    see all

  • Function

    Promotes endocytosis, possesses opsonic properties and influences the mineral phase of bone. Shows affinity for calcium and barium ions.

  • Tissue specificity

    Synthesized in liver and selectively concentrated in bone matrix. Secreted in plasma. It is also found in dentin in much higher quantities than other plasma proteins.

  • Sequence similarities

    Belongs to the fetuin family.
    Contains 2 cystatin fetuin-A-type domains.

  • Post-translational
    modifications

    Phosphorylation sites are present in the extracelllular medium.

  • Cellular localization

    Secreted.
  • Information by UniProt

Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols

References (0)

Publishing research using ab93727? Please let us know so that we can cite the reference in this datasheet.

ab93727 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Question

Hi I am interested in buying ab93727 Alpha 2 HS Glycoprotein ASGPR. Do you have any more information on this product? For example an SDS-PAGE gel? Also, are you able to tell me how it relates to Asialofetuin?   Perhaps there is someone that I can talk to about this?  

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Answer

Thank you for your email and call. I am sending you an image of ab93727 on a SDS gel. Please note the different bands sizes in reducing and non reducing gels. Based on a literature review I believe that asialofetuin refers to alpha-2-HS-glycoprotein in bovine, but the equivalent gene in human is alpha-2-HS-glycoprotein otherwise known as fetuin-A. I can now confirm that this protein is in its native status and therefore might be suitable for a functional assay. But to our knowledge, ab93727 has not been tested in functional competition assays. Therefore, I can offer a discount off a future purchase if you buy ab93727 now, test it in functional competition assays and submit feedback to us in the form of an Abreview. It doesn’t matter whether the Abreview is positive or negative, we would just really like to receive your feedback. The discount would be to the value of 1 free primary antibody. If you are interested in this offer, please follow these steps: 1. Reply to this e-mail to let me know that you would like to proceed and test ab93727 in functional competition assays. I will then send a discount code. This code must be issued before purchasing ab93727 so please wait for my reply before ordering. 2. Purchase ab93727 either by phone, fax, or online (www.abcam.com). 3. Test it in functional competition assays. 4. Let us know the results, positive or negative, using our Abreview system (this will take about 10 minutes and images are great if you have them!). To find out how to submit an Abreview, please visit: https://www.abcam.com/abreviews. 5. After the review is submitted to us, the discount code becomes active. Simply place your new order by phone, fax, or on the web and mention the discount code. The discount can be redeemed for any primary antibody ordered and the discount code is valid for 4 months after issue. We are always pleased to obtain feedback about our products and any information is greatly appreciated! Even if ab93727 turns out to be unsuitable for functional competition assays, you will still receive the discount on your next purchase after your Abreview has been submitted. Please let me know if you have any questions about this offer and I would be happy to help you further. The Terms and Conditions of this offer can be found at: www.abcam.com/collaborationdiscount.

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