Description

  • Product name

    Native Human Alpha Thrombin protein
    See all Alpha Thrombin proteins and peptides
  • Biological activity

    <0.1% Thrombin activity. Assay is performed to determine percent contaminating thrombin activity. Residual thrombin activity is based on a thrombin standard curve. Chromagenic assay uses Spectrozyme-TH as substrate.
  • Purity

    > 95 % SDS-PAGE.

  • Expression system

    Native
  • Protein length

    Full length protein
  • Animal free

    No
  • Nature

    Native
    • Species

      Human
    • Predicted molecular weight

      37 kDa
    • Amino acids

      328 to 622

Specifications

Our Abpromise guarantee covers the use of ab81585 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Form

    Liquid
  • Additional notes

    The active site of thrombin is blocked with DFP (Diisopropylfluorophosphate).

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 7.40
    Constituents: 0.476% HEPES, 0.87% Sodium chloride

General Info

  • Alternative names

    • Coagulation factor II
    • Coagulation factor II (thrombin)
    • F2
    • prothrombin B-chain
    • PT
    • serine protease
    see all
  • Relevance

    Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing.
  • Cellular localization

    Secreted › extracellular space.

References

ab81585 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab81585.
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