Description

  • Product name

  • Purity

    > 95 % SDS-PAGE.
    ab77903 is purified by Column chromatography. There is a single arc by IEP against whole human serum.
  • Expression system

    Native
  • Protein length

    Full length protein
  • Animal free

    No
  • Nature

    Native
    • Species

      Human

Associated products

Specifications

Our Abpromise guarantee covers the use of ab77903 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Form

    Lyophilised
  • Additional notes

    All human source materials have tested negative for HIV 1, HIV 2, anti-HCV, anti-HBc antibodies and HBsAg. No test guarantees a product to be non-infectious. Therefore, all material derived from human fluids or tissues should be considered as potentially infectious.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.

    pH: 10.00
    Constituents: 0.53% Sodium carbonate, 0.415% Sodium deoxycholate, 0.29% Sodium chloride

  • Reconstitution
    Reconstitute with 147ul distilled water.

General Info

  • Alternative names

    • Apo B
    • Apo B 100
    • Apo B-100
    • Apo B-48
    • Apo B100
    • Apo B48
    • APOB
    • ApoB 100
    • ApoB 48
    • APOB_HUMAN
    • Apolipoprotein B
    • Apolipoprotein B (including Ag(x) antigen)
    • Apolipoprotein B 100
    • Apolipoprotein B 48
    • Apolipoprotein B-48
    • Apolipoprotein B100
    • Apolipoprotein B48
    • FLDB
    • LDLCQ4
    see all
  • Function

    Apolipoprotein B is a major protein constituent of chylomicrons (apo B-48), LDL (apo B-100) and VLDL (apo B-100). Apo B-100 functions as a recognition signal for the cellular binding and internalization of LDL particles by the apoB/E receptor.
  • Involvement in disease

    Hypobetalipoproteinemia, familial, 1
    Familial ligand-defective apolipoprotein B-100
    Defects in APOB associated with defects in other genes (polygenic) can contribute to hypocholesterolemia.
  • Sequence similarities

    Contains 1 vitellogenin domain.
  • Post-translational
    modifications

    Palmitoylated; structural requirement for proper assembly of the hydrophobic core of the lipoprotein particle.
  • Cellular localization

    Cytoplasm. Secreted.
  • Information by UniProt

References

This product has been referenced in:

  • Disterer P  et al. Exon Skipping of Hepatic APOB Pre-mRNA With Splice-switching Oligonucleotides Reduces LDL Cholesterol In Vivo. Mol Ther 21:602-9 (2013). WB . Read more (PubMed: 23319054) »
See 1 Publication for this product

Customer reviews and Q&As

Answer

Thank you for your enquiry and your interest in our products. I can confirm that all these 3 products (ab77859, ab77903, ab82277) do not have Apo B-48. I hope this information will be useful for you.

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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