Product nameNative Human Apolipoprotein B
See all Apolipoprotein B proteins and peptides
Purity> 95 % SDS-PAGE.
Protein lengthFull length protein
Our Abpromise guarantee covers the use of ab91112 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Additional notesPrepared from fresh, non-frozen plasma shown to be non reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests.
Concentration information loading...
Preparation and Storage
Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Constituents: 0.53% Sodium carbonate, 0.415% Sodium deoxycholate, 0.29% Sodium chloride
- Apo B
- Apo B 100
- Apo B-100
FunctionApolipoprotein B is a major protein constituent of chylomicrons (apo B-48), LDL (apo B-100) and VLDL (apo B-100). Apo B-100 functions as a recognition signal for the cellular binding and internalization of LDL particles by the apoB/E receptor.
Involvement in diseaseHypobetalipoproteinemia, familial, 1
Familial ligand-defective apolipoprotein B-100
Defects in APOB associated with defects in other genes (polygenic) can contribute to hypocholesterolemia.
Sequence similaritiesContains 1 vitellogenin domain.
modificationsPalmitoylated; structural requirement for proper assembly of the hydrophobic core of the lipoprotein particle.
Cellular localizationCytoplasm. Secreted.
- Information by UniProt
SDS-PAGE: 4-12% Bis-Tris-HCI NuPAGE gel
Lane 1. 5 μg Apolipoprotein (reduced /heated)
Lane 2. 10 μg Apolipoprotein (reduced/ heated)
Lane 3. 20 μg Apolipoprotein (reduced/ heated)
Lane 4. Molecular weight markers
Lane 5. 5 μg Apolipoprotein (non-reduced/no heat)
Lane 6. 10 μg Apolipoprotein (non-reduced/no heat)
Lane 7. 20 μg Apolipoprotein (non-reduced/no heat)
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab91112 has not yet been referenced specifically in any publications.