Description

  • Product name

    Native Human Histones protein
    See all Histones proteins and peptides
  • Purity

    > 95 % SDS-PAGE.

  • Expression system

    Native
  • Protein length

    Full length protein
  • Animal free

    No
  • Nature

    Native
    • Species

      Human
    • Additional sequence information

      Other Immunogen Type. Highly purified mixture of Human core histones (H2A, H2B, H3, and H4) isolated via hydroxyapatite chromatography from HeLa S3 (human cervical adenocarcinoma) nuclear pellet.

Specifications

Our Abpromise guarantee covers the use of ab176964 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Form

    Liquid
  • Additional notes

    Highly purified mixture of human core histones (H2A, H2B, H3, and H4) isolated via hydroxyapatite chromatography from HeLa S3 (human cervical adenocarcinoma) nuclear pellet.

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on Dry Ice. Store at -80°C. Avoid freeze / thaw cycle.

    pH: 6.90
    Constituents: 0.82% Sodium phosphate, 0.58% Sodium chloride, 0.0078% Beta mercaptoethanol

General Info

  • Alternative names

    • H1
    • H1.5
    • H1F5
    • H2A
    • H2B
    • H3
    • H4
    see all
  • Relevance

    Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures.
  • Cellular localization

    Nuclear

Images

  • SDS-PAGE analysis of ab176964
    Lane 1: Markers:
    Lane 2: ab176964 (1 μg)
    Lane 3: ab176964 (2 μg)

References

ab176964 has not yet been referenced specifically in any publications.

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